keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
説明 | Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. |
ターゲット&IC50 | Bradykinin B2:0.798 nM(ki), Bradykinin B2:1.07 nM |
In vitro | Icatibant is a decapeptide resistant to the bradykinin-degrading proteases, leading to a longer half-life than bradykinin which it antagonizes[1]. |
In vivo | Icatibant treatment exhibits efficacy in bradykinin-mediated angioedema attacks, and rapidly relieves symptom [1]. |
分子量 | 1364.57 |
分子式 | C61H93N19O15S |
CAS No. | 138614-30-9 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (73.28 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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