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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T35593 | Semapimod tetrahydrochloride | CPSI-2364 tetrahydrochloride | TLR , MAPK |
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microgl... | |||
T79304 | Semapimod | CPSI-2364,CNI-1493 free base | |
Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6. It hinders TLR4 signaling with an IC50 of approximately 0.3 μM, impedes p38 MAPK, and reduces nitric oxide ... |