|
T71832 |
CTX-0124143
|
|
Histone Acetyltransferase
|
|
CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence. |
|
T2042 |
CTX-0294885
|
|
Others
|
|
CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent. |
|
TP1289 |
Cardiotoxin Analog (CTX) IV (6-12) TFA
|
Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE) |
Others
|
|
Cardiotoxin Analog IV (6-12) TFA, a partial peptide of Cardiotoxin Analog IV, is derived from the venom of the Taiwan Cobra, showcasing the unique properties of snake venom cardiotoxin[1]. |
|
T3715 |
Acebilustat
|
CTX-4430 |
Aminopeptidase
,
LTR
|
|
Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor. |
|
T9167 |
PF-9363
|
CTX-3648 |
Histone Acetyltransferase
|
|
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer. |
|
TP1455 |
Cardiotoxin Analog (CTX) IV (6-12)
|
Cardiotoxin Analog (CTX) IV 6-12 |
|
|
Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. |
|
T19251 |
CTX-0294885 hydrochloride (1439934-41-4 free base)
|
CTX-0294885 hydrochloride |
Others
|
|
CTX-0294885 hydrochloride is an agarose-supported kinase capture reagent. |
|
T82664 |
CTX-2026
|
|
|
|
CTX-2026, a fully human antibody, targets and binds to CD277, demonstrating an anti-tumor effect in ovarian tumor models, and is utilized in cancer research [1]. |
|
T62049 |
CTX-712
|
|
Others
|
|
CTX-712 is a potent inhibitor of cdc2-like kinase ( CLK ). CTX-712 inhibits inhibits cancer survival and cancer cell growth. |
|
T76734 |
CTX-471
|
|
|
|
CTX-471, a fully human monoclonal antibody targeting CD137, exhibits binding affinity for CD137 across multiple species, including humans, cynomolgus macaques, and mice, with dissociation constant (Kd) values of 50 nM, 6... |
|
T72214 |
CTX-0294885 hydrochloride
|
|
Others
|
|
CTX-0294885 hydrochloride is a broad-spectrum kinase inhibitor capable of capturing 235 kinases from MDA-MB-231 cells, including all members of the AKT family. This compound serves as a potent tool for analyzing kinome s... |
|
T23707 |
Alpha-Conotoxin imi
|
alpha-Ctx-imi |
|
|
alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand. |
|
T15016 |
CTX1
|
|
p53
|
|
CTX1 is a small molecule activator of p53. |
|
T4584 |
BMS-813160
|
BMS 813160 |
CCR
|
|
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular. |
|
T60050 |
ANT3310
|
|
Antibacterial
|
|
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection. |
|
T38941 |
FPI-1523 sodium
|
|
Endogenous Metabolite
,
Antibacterial
|
|
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with K d s of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively.FPI-1523 sodium inhibited PBP2 with an IC 50 of 3.2 μM.FPI-1523 sodium has ... |
|
T10422 |
Avibactam free acid
|
NXL-104 free acid |
Antibacterial
|
|
Avibactam (NXL-104) free acid is a covalent and reversible inhibitor of non-β-lactam β-lactamase (IC50s: 8 nM and 5 nM for β-lactamase TEM-1 and CTX-M-15). |
|
T10713 |
CCR4 antagonist 2
|
|
Calcium Channel
|
|
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the n... |
|
T39661 |
CCR4 antagonist 3
|
CCR4 antagonist 3 |
Others
|
|
CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antago... |
|
T38940 |
FPI-1523
|
|
Others
|
|
FPI-1523, a derivative of Avibactam, is a potent inhibitor of β-lactamase enzymes. It has Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. Additionally, FPI-1523 inhibits PBP2 with an IC50 of 3.2 μM and... |
|
T60711 |
Avibactam sodium hydrate
|
|
Others
|
|
Avibactam sodium hydrate (NXL-104 hydrate) is a covalent and reversible inhibitor of β-lactamase that does not contain a β-lactam core. Avibactam sodium hydrate inhibits β-lactamase CTX-M-15 and TEM-1 with IC 50 s of 5 n... |
|
T39662 |
CCR4 antagonist 3 hydrochloride
|
|
Others
|
|
CCR4 antagonist 3 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assa... |
|
T60874 |
Avibactam sodium dihydrate
|
|
Others
|
|
Avibactam sodium (NXL-104) dihydrate inhibits CTX-M-15 and β-lactamase TEM-1 with IC 50 s of 5 nM and 8 nM, respectively. Avibactam sodium dihydrate is a reversible and covalent inhibitor of non-β-lactam β-lactamase [1]. |
|
T73902 |
Desacetylcefotaxime
|
|
Others
|
|
Desacetylcefotaxime, an in vivo metabolite of Cefotaxime (CTX), exhibits noteworthy in vitro antimicrobial efficacy, akin to its parent compound, against a broad spectrum of aerobic and anaerobic bacteria [1]. |
|
T61204 |
FPI-1465
|
|
Others
|
|
FPI-1465 is a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs), demonstrating inhibition of PBP2 with an IC50 of 1.0 μg/mL. Additionally, it exhibits activity against β-lactamase CTX-M-15 and ... |
