| T82008 |
JG-2016
|
2887480-87-5
|
98%
|
|
|
JG-2016, as a small molecule histone acetyltransferase 1 (HAT1) inhibitor, inhibits the growth of human cancer cell lines, inhibits enzyme activity in cellulose,...
|
| T3217 |
PF-CBP1 hydrochloride
|
2070014-93-4
|
|
|
|
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains w...
|
| T9167 |
PF-9363
|
2569009-58-9
|
|
|
|
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.
|
| T6133 |
Remodelin hydrobromide
|
1622921-15-6
|
|
|
|
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
|
| T4679 |
WM-1119
|
2055397-28-7
|
|
|
|
WM-1119 is a highly potent, selective KAT6A/B inhibitor
|
| T11563 |
Histone Acetyltransferase Inhibitor II
|
932749-62-7
|
100%
|
|
|
Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activity in...
|
| T15216 |
EML 425
|
1675821-32-5
|
100%
|
|
|
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)/p300 (IC50s: 2.9 and 1.1 μM, respectively).
|
| T27083 |
Crebinostat
|
1092061-61-4
|
94.96%
|
|
|
Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respect...
|
| T9102 |
WM-3835
|
2229025-70-9
|
97.47%
|
|
|
WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferati...
|
| T28471 |
PU139
|
158093-65-3
|
97.61%
|
|
|
PU139 is a novel inhibitor of histone acetyltransferase (HAT).
|
| T9373 |
DCH36_06
|
593273-05-3
|
98.32%
|
|
|
DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) as a bona fide is a potent p30...
|
| T14073 |
A-485
|
1889279-16-6
|
98.32%
|
|
|
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).
|
| T8658 |
NEO2734
|
2081072-29-7
|
98.56%
|
|
|
NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
|
| T11366 |
Garcinol
|
78824-30-3
|
98.59%
|
|
|
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-...
|
| T11807 |
L002
|
321695-57-2
|
98.59%
|
|
|
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket a...
|
| T6389 |
Anacardic Acid
|
16611-84-0
|
98.84%
|
|
|
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial...
|
| T1516 |
Curcumin
|
458-37-7
|
98.98%
|
|
|
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide...
|
| T6668 |
SGC-CBP30
|
1613695-14-9
|
99.03%
|
|
|
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
|
| T3969 |
I-CBP112
|
1640282-31-0
|
99.1%
|
|
|
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.
|
| T6584 |
MG 149
|
1243583-85-8
|
99.1%
|
|
|
MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
|
