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T4577 |
Cariprazine
|
RGH-188 |
Dopamine Receptor
,
5-HT Receptor
|
|
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
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T8382 |
Cariprazine hydrochloride
|
Cariprazine HCl,RGH188 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
|
|
Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively) |
|
T15117 |
Didesmethyl cariprazine
|
|
Dopamine Receptor
,
5-HT Receptor
|
|
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3/D2 receptor partial agonist of do... |
|
T15100 |
Desmethyl cariprazine
|
|
Dopamine Receptor
,
5-HT Receptor
|
|
Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A... |
|
T10681 |
Cariprazine D6
|
RGH-188 D6 |
Dopamine Receptor
|
|
Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM). |
