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Search Results for " Cortisol "

ターゲット

25

阻害剤

11

天然化合物

11

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T0270 Hydrocortisone 17-butyrate Cortisol 17-butyrate,Hydrocortisone butyrate Glucocorticoid Receptor , Annexin A , Adrenergic Receptor
Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
T75683 Cortisol sulfate sodium
Cortisol sulfate sodium (Cortisol 21-sulfate), a Cortisol metabolite, serves as a specific ligand for intracellular transcortin [1] [2] [3].
T21865 BC 11-38 PDE
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).
TP1031 Tetracosactide Tetracosactrin Others
Tetracosactide (Tetracosactrin) (INN) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.
T35664 Tetracosactide acetate Others
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland.
T73794 18-Hydroxycortisol
18-Hydroxycortisol, a cortisol derivative and steroidogenic intermediate, is an endogenous steroid secreted by the adrenal cortex. It serves as a useful biochemical marker in primary aldosteronism (PA) research [1].
T21253 5-alpha-Hydroxy-Laxogenin Others
5-alpha-Hydroxy-Laxogenin is an stress hormone cortisol inhibitor
T16510 PF-915275 Dehydrogenase
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11β-hydroxyster...
TP1248L ACTH 11-24 acetate(4237-93-8 free base) Adrenocorticotropic Hormone (11-24) acetate Melanocortin Receptor
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH ...
TP1238L ACTH 1-14 acetate(25696-21-3 free base) Adrenocorticotropic Hormone Fragment 1-14 acetate Adrenergic Receptor
ACTH 1-14 acetate(25696-21-3 free base) (Adrenocorticotropic Hormone Fragment 1-14 acetate) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also...
T25443 FW 34569 FW-34-569,FW34569,FW 34-569,FW-34569,FW34-569
FW 34569 is an enkephalin analogue. It stimulated growth hormones and prolactin release and inhibited the release of cortisol and LH, while FSH remained unchanged.
TP1238 ACTH (1-14) ACTH 1-14,Adrenocorticotropic Hormone Fragment 1-14
ACTH (1-14), a fragment of adrenocorticotropin, governs the production of cortisol and androgens.
TP1237 ACTH (1-14) TFA (25696-21-3 free base) Adrenocorticotropic Hormone Fragment 1-14 (TFA),ACTH (1-14) TFA
ACTH (1-14) (TFA) is a polypeptide of corticotrophin, which promotes the release of cortisol.
TP1248 ACTH (11-24) ACTH 11-24,Adrenocorticotropic Hormone (11-24)
ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
T73664 Adrenocorticotropic hormone TFA
Adrenocorticotropic hormone (ACTH) TFA, a polypeptide tropic hormone synthesized by the anterior pituitary gland, regulates the production of cortisol and androgens [1] [2].
T36927 Hydrocortisone phosphate
Hydrocortisone phosphate is the pharmaceutical term for cortisol, which is a steroid hormone, in the glucocorticoid class of hormones, increases blood sugar through gluconeogenesis, to suppress the immune system, and to ...
T75979 ACTH (11-24) (acetate)
ACTH (11-24) (acetate), a fragment of adrenocorticotropic hormone (ACTH), functions as a receptor antagonist and promotes cortisol release. This compound is utilized in researching the central nervous system [1].
T75985 ACTH (1-14) (TFA)
ACTH (1-14) (TFA) is a regulatory fragment of adrenocorticotropin, specifically involved in the control of cortisol and androgen synthesis [1].
T61593 11β-HSD1-IN-6
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their ...
T73663 Adrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH), a polypeptide tropic hormone secreted by the anterior pituitary gland, regulates cortisol and androgen production [1] [2].
T64249 CYP11B1-IN-2
CYP11B1-IN-2 (compound 7aa) is a selective, orally active inhibitor of CYP11B1 that acts on human CYP11B1 (IC50: 9 nM) and rat CYP11B1 (IC50: 25 nM). CYP11B1-IN-2 can be used to study diseases caused by cortisol overload...
T76595 (Des-His6)-ACTH (1-24) (human, bovine, rat)
(Des-His^6)-ACTH (1-24) (human, bovine, rat) is an adrenocorticotropic hormone (ACTH) analog. Produced by the anterior pituitary gland, ACTH is a polypeptide tropic hormone that regulates the production of cortisol and a...
T70763 KR-67607
KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat ...
T76591 (Des-Glu5)-ACTH (1-24) (human, bovine, rat)
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an adrenocorticotropic hormone (ACTH) analogue, synthesized by the anterior pituitary gland to regulate cortisol and androgen production [1]. This polypeptide tropic hormone...
T35993 Epitalon (acetate)
Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalo...

Compounds

Hydrocortisone 17-butyrate
T0270
Synonym: Cortisol 17-butyrate,Hydrocortisone butyrate
Target: Glucocorticoid Receptor, Annexin A, Adrenergic Receptor
Cortisol sulfate sodium
T75683
Synonym:
Target:
BC 11-38
T21865
Synonym:
Target: PDE
Tetracosactide
TP1031
Synonym: Tetracosactrin
Target: Others
Tetracosactide acetate
T35664
Synonym:
Target: Others
18-Hydroxycortisol
T73794
Synonym:
Target:
5-alpha-Hydroxy-Laxogenin
T21253
Synonym:
Target: Others
PF-915275
T16510
Synonym:
Target: Dehydrogenase
ACTH 11-24 acetate(4237-93-8 free base)
TP1248L
Synonym: Adrenocorticotropic Hormone (11-24) acetate
Target: Melanocortin Receptor
ACTH 1-14 acetate(25696-21-3 free base)
TP1238L
Synonym: Adrenocorticotropic Hormone Fragment 1-14 acetate
Target: Adrenergic Receptor
FW 34569
T25443
Synonym: FW-34-569,FW34569,FW 34-569,FW-34569,FW34-569
Target:
ACTH (1-14)
TP1238
Synonym: ACTH 1-14,Adrenocorticotropic Hormone Fragment 1-14
Target:
ACTH (1-14) TFA (25696-21-3 free base)
TP1237
Synonym: Adrenocorticotropic Hormone Fragment 1-14 (TFA),ACTH (1-14) TFA
Target:
ACTH (11-24)
TP1248
Synonym: ACTH 11-24,Adrenocorticotropic Hormone (11-24)
Target:
Adrenocorticotropic hormone TFA
T73664
Synonym:
Target:
Hydrocortisone phosphate
T36927
Synonym:
Target:
ACTH (11-24) (acetate)
T75979
Synonym:
Target:
ACTH (1-14) (TFA)
T75985
Synonym:
Target:
11β-HSD1-IN-6
T61593
Synonym:
Target:
Adrenocorticotropic hormone
T73663
Synonym:
Target:
CYP11B1-IN-2
T64249
Synonym:
Target:
(Des-His6)-ACTH (1-24) (human, bovine, rat)
T76595
Synonym:
Target:
KR-67607
T70763
Synonym:
Target:
(Des-Glu5)-ACTH (1-24) (human, bovine, rat)
T76591
Synonym:
Target:
Epitalon (acetate)
T35993
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
T1614 Hydrocortisone Cortisol Glucocorticoid Receptor , Endogenous Metabolite
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio...
T36472 Tetrahydro-11-deoxy Cortisol
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cyto...
T1243 Hydrocortisone acetate Cortisol 21-acetate,Hydrocortisone 21-acetate Glucocorticoid Receptor , Annexin A , Endogenous Metabolite
Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
T75682 Cortisol sulfate
Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol . Cortisol sulfate is a specific ligand for intracellular transcortin [1] [2] [3] .
T13517 Allotetrahydrocortisol 5a-Tetrahydrocortisol Others
Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.
T17057 Tetrahydrocortisol Others
The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase activity. Tetrahydrocortisol is cortisol metabolite.
T39991 18-Oxocortisol
18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
T36915 21-Deoxycortisol
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital a...
T2748 Cortodoxone 11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol Glucocorticoid Receptor , Endogenous Metabolite
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
T2884 Cortisone Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone Glucocorticoid Receptor , Endogenous Metabolite
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.
T0034 Cortisone acetate Cortisone 21-acetate,NSC 49420 Glucocorticoid Receptor , Endogenous Metabolite
Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02107 Cortisol Binding Globulin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Cortisol Binding Globulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is Q06770.
TMPY-02041 Cortisol Binding Globulin Protein, Human, Recombinant (His) Human HEK293 Cells
Cortisol Binding Globulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is A0A2Z4LCH4.
TMPY-06702 Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.54 kDa and the accession number is Q06770.
TMPY-05329 Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.9 kDa and the accession number is A0A2Z4LC...
TMPH-00844 HSD11B2 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HS...
TMPH-00843 HSD11B1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one ...
TMPY-01660 SULT1E1 Protein, Human, Recombinant (His) Human E. coli
Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catal...
TMPH-02139 CYP17A1 Protein, Human, Recombinant (GST) Human E. coli
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen sy...
TMPY-06836 NR3C1 Protein, Human, Recombinant (His) Human E. coli
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ...
TMPY-01893 Serpin A12 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin,...
TMPY-01855 Serpin A10 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPI...