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Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T0293 Metyrapone 54-36-4 98%
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the ...
T0809 Dicoumarol 66-76-2 98%
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
T14388 AZD 4017 1024033-43-9 98%
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
T15551 IDH889 1429179-07-6 98%
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
T15173 DSM265 1282041-94-4 98%
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be...
T9974 Antiproliferative agent-13 663214-48-0 98%
Antiproliferative agent-13 is a compound with antiproliferative activity.
TJS1382 Taraxerone 514-07-8 98%
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease i...
T3444 Merimepodib 198821-22-6 98%
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
T37190 L-Allylglycine 16338-48-0 98%
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
T40686 Tiazofurin 60084-10-8 98%
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenin...
T1809 AGI-6780 1432660-47-3 98%
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
T0897 Nitrofurazone 59-87-0 98%
Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJ...
T12438 PfDHODH-IN-1 183945-55-3 98%
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
T10146 4-Hydroxyderricin 55912-03-3 98%
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
T12196 NCT-505 2231079-74-4 98%
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC...
T77576 17β-HSD10-IN-1 2316765-78-1 98%
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of A...
T0494 Tetramisole hydrochloride 5086-74-8 98%
Tetramisole hydrochloride (Tetramisole HCl) inhibits alkaline phosphatase and is a high-purity antiparasitic agent.
T9494 Imidazole-5-propionic acid 1074-59-5 98%
Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination. Imidazole-5-propionic aci...
T73446 BI‑3231 2894848-07-6 98%
BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study...
T73143 PHGDH-IN-3 2893778-31-7 98%
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about can...
Metyrapone
T0293
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the ...
Dicoumarol
T0809
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
AZD 4017
T14388
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
IDH889
T15551
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
DSM265
T15173
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be...
Antiproliferative agent-13
T9974
Antiproliferative agent-13 is a compound with antiproliferative activity.
Taraxerone
TJS1382
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease i...
Merimepodib
T3444
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
L-Allylglycine
T37190
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
Tiazofurin
T40686
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenin...
AGI-6780
T1809
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
Nitrofurazone
T0897
Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJ...
PfDHODH-IN-1
T12438
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
4-Hydroxyderricin
T10146
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
NCT-505
T12196
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC...
17β-HSD10-IN-1
T77576
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of A...
Tetramisole hydrochloride
T0494
Tetramisole hydrochloride (Tetramisole HCl) inhibits alkaline phosphatase and is a high-purity antiparasitic agent.
Imidazole-5-propionic acid
T9494
Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination. Imidazole-5-propionic aci...
BI‑3231
T73446
BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study...
PHGDH-IN-3
T73143
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about can...
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