検索結果

Search Results for " Deoxycytidine Kinase "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T50079	Antitumor agent-152		Others
	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine can be used in the development of new deoxycytidine kinase (dCK) inhibitors.		Others
T6501	Fludarabine Phosphate	NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T39114	DI-82		Others
	DI-82 is a highly potent inhibitor of deoxycytidine kinase (dCK), displaying impressive biochemical activity with an IC50 value of 27.8 nM and a K i value of 9.2 nM. Additionally, DI-82 exhibits significant antitumor eff...		Others
T39550	DI-87		Others
	DI-87 is a potent, orally active deoxycytidine kinase (dCK) inhibitor with high selectivity and an EC 50 of 10.2 nM. With demonstrated antitumor efficacy, DI-87 is employed in combination therapy specifically targeting t...		Others
T68917	Fazarabine		Others
	Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph...		Others
T84932	Cytarabine 5′-monophosphate	ara-CMP	Others
	Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibi...		Others
T15378	Gemcitabine elaidate	Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126	Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
	Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel...		Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy

Compounds

Fludarabine Phosphate

T6501

Synonym: NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cytarabine 5′-monophosphate

Synonym: Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Autophagy

カタログ番号	製品名	別名	ターゲット
T4731	2'-Deoxycytidine-5'-monophosphoric acid	dCMP,2'-Deoxycytidine 5'-monophosphate	Others , Endogenous Metabolite
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation t...		Others , Endogenous Metabolite
T4972	2'-Deoxycytidine-5'-diphosphate trisodium	dCDP	Endogenous Metabolite
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription.		Endogenous Metabolite

天然物製品

2'-Deoxycytidine-5'-monophosphoric acid

T4731

Synonym: dCMP,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

2'-Deoxycytidine-5'-diphosphate trisodium

T4972

Synonym: dCDP

Target: Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00922	DCK Protein, Human, Recombinant (His & T7)	Human	E. coli
	Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanos...

DCK Protein, Human, Recombinant (His & T7)

TMPJ-00922

Species: Human

Expression System: E. coli