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Search Results for " EN-6 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T11191	EN6		Proton pump , Autophagy
	EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP-43 aggregates, a causative ...		Proton pump , Autophagy
T25150	BI-69A11	BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one	NF-κB , Akt
	BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...		NF-κB , Akt
T126063	8-Oxoeremophil-6-en-12-oic aicd
	8-Oxoeremophil-6-en-12-oic aicd is a useful organic compound for research related to life sciences and the catalog number is T126063.
T124161	5α,8α-Epidioxyergost-6-en-3β-ol
	5α,8α-Epidioxyergost-6-en-3β-ol is a useful organic compound for research related to life sciences and the catalog number is T124161.
T123873	6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one
	6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one is a useful organic compound for research related to life sciences and the catalog number is T123873.
TNU0739	(-)-(1S,5R)-cis-Bicyclo[3.2.0]hept-2-en-6-one
	Building block - others
TNU0847	6-[[(3b)-Cholest-5-en-3-yl]oxy]-1-hexanol
	Intermediate and Building Blocks - Nucleophile; Scaffolds and Templates
T130192	3,5,7-Trihydroxy-p-menth-1-en-6-one, 5-Tigloyl, 3
	3,5,7-Trihydroxy-p-menth-1-en-6-one, 5-Tigloyl, 3 is a useful organic compound for research related to life sciences and the catalog number is T130192.
T125520	(S,E)-2-Methyl-6-(p-tolyl)hept-3-en-2-ol
	(S,E)-2-Methyl-6-(p-tolyl)hept-3-en-2-ol is a useful organic compound for research related to life sciences and the catalog number is T125520.
T65075	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate
	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate is a useful organic compound for ...
TNU0846	Chlolest-5-en-3β-tosylate; Cholest-5-en-3-ol (3β)-(4-methylbenzenesulfonate)
	Chlolest-5-en-3β-tosylate; Cholest-5-en-3-ol (3β)-(4-methylbenzenesulfonate) is a useful organic compound for research related to life sciences. The catalog number is TNU0846 and the CAS number is 1182-65-6.
T69766	Gusacitinib HCl
	Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed ...
T37419	Zetomipzomib
	KZR-616, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616 has the potential f...

Compounds

EN6

T11191

Synonym:

Target: Proton pump, Autophagy

BI-69A11

T25150

Synonym: BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one

Target: NF-κB, Akt

8-Oxoeremophil-6-en-12-oic aicd

T126063

Synonym:

Target:

5α,8α-Epidioxyergost-6-en-3β-ol

T124161

Synonym:

Target:

6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one

T123873

Synonym:

Target:

(-)-(1S,5R)-cis-Bicyclo[3.2.0]hept-2-en-6-one

TNU0739

Synonym:

Target:

6-[[(3b)-Cholest-5-en-3-yl]oxy]-1-hexanol

TNU0847

Synonym:

Target:

3,5,7-Trihydroxy-p-menth-1-en-6-one, 5-Tigloyl, 3

T130192

Synonym:

Target:

(S,E)-2-Methyl-6-(p-tolyl)hept-3-en-2-ol

T125520

Synonym:

Target:

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate

T65075

Synonym:

Target:

Chlolest-5-en-3β-tosylate; Cholest-5-en-3-ol (3β)-(4-methylbenzenesulfonate)

カタログ番号	製品名	別名	ターゲット
TN6832	Sulcatone	6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one	Endogenous Metabolite
	Sulcatone (6-Methyl-5-hepten-2-one) is an alarm/panic pheromone produce by ant species.		Endogenous Metabolite
TN2584	11-Hydroxydrim-7-en-6-one		Others
	11-Hydroxydrim-7-en-6-one is a natural product for research related to life sciences. The catalog number is TN2584 and the CAS number is 74635-87-3.		Others
TN1214	2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one	Others
	2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one is a natural product		Others
TN3332	9alpha,11-Dihydroxydrim-7-en-6-one		Others
	9alpha,11-Dihydroxydrim-7-en-6-one is a natural product for research related to life sciences. The catalog number is TN3332 and the CAS number is 127681-58-7.		Others
TN5861	3-Hydroxy-p-menth-1-en-6-one	(3R,4S)-3-Hydroxy-p-menth-1-en-6-one
	3-Hydroxy-p-menth-1-en-6-one is a natural product for research related to life sciences. The catalog number is TN5861 and the CAS number is 61570-82-9.
TN3331	9alpha,11,12-Trihydroxydrim-7-en-6-one		Others
	9alpha,11,12-Trihydroxydrim-7-en-6-one is a natural product for research related to life sciences. The catalog number is TN3331 and the CAS number is 192566-65-7.		Others
TN6357	5-Hydroxy-1,7-diphenylhept-6-en-3-one
	5-Hydroxy-1,7-diphenylhept-6-en-3-one is a natural product for research related to life sciences. The catalog number is TN6357 and the CAS number is 155239-30-8.
TN2514	1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one		Others
	1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one is a natural product for research related to life sciences. The catalog number is TN2514 and the CAS number is 1251830-57-5.		Others
TN2513	1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol		Others
	1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol is a natural product from Alpinia galanga.		Others
TN2994	4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one		Others
	4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a natural product for research related to life sciences. The catalog number is TN2994 and the CAS number is 170380-68-4.		Others
TN3068	4\|A,6\|A-Dihydroxyeudesm-11(13)-en-12,8\|A-olide	4alpha,6alpha-Dihydroxyeudesm-11(13)-en-12,8beta-olide	Others
	4\|A,6\|A-Dihydroxyeudesm-11(13)-en-12,8\|A-olide is a natural product for research related to life sciences. The catalog number is TN3068 and the CAS number is 35001-19-5.		Others
TN3141	6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one		Others
	6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one is a natural product for research related to life sciences. The catalog number is TN3141 and the CAS number is 949081-05-4.		Others
TN2471	1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol		Others
	1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol is a natural product for research related to life sciences. The catalog number is TN2471 and the CAS number is 1206788-61-5.		Others
TN6909	Polyporusterone B	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...		Others
TN5870	1,8-Dihydroxy-p-menth-3-en-2-one	6-Hydroxy-3-(2-hydroxypropan-2-yl)-6-methylcyclohex-2-en-1-one
	1,8-Dihydroxy-p-menth-3-en-2-one is a natural product for research related to life sciences. The catalog number is TN5870 and the CAS number is 1392224-56-4.
TN6864	Prosaikogenin F	(2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3...		Others
TN6498	Stevia impurity (13-[(2-O-6-deoxy-Î²-D-glucopyranosyl-3-O-Î²-D-glucopyranosyl-Î²-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid Î²-D-glucopyranosyl ester)
	Stevia impurity (13-[(2-O-6-deoxy-Î²-D-glucopyranosyl-3-O-Î²-D-glucopyranosyl-Î²-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid Î²-D-glucopyranosyl ester) is a natural product for research related to life sciences. The ...
TN1201	25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside	(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside	Others
	(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside is a natural product		Others
TN2512	1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one		Others
	1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one is a natural product of Alpinia, Zingiberaceae. The catalog number is TN2512 and the CAS number is 1083200-79-6. 1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one can be used as a reference ...		Others
TN3755	Dammar-20(21)-en-3,24,25-triol		Others
	Dammar-20(21)-en-3,24,25-triol is a natural product for research related to life sciences. The catalog number is TN3755 and the CAS number is 55050-69-6.		Others

天然物製品

Sulcatone

TN6832

Synonym: 6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one

Target: Endogenous Metabolite

11-Hydroxydrim-7-en-6-one

TN2584

Synonym:

Target: Others

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one

TN1214

Synonym: 2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one

Target: Others

9alpha,11-Dihydroxydrim-7-en-6-one

TN3332

Synonym:

Target: Others

3-Hydroxy-p-menth-1-en-6-one

TN5861

Synonym: (3R,4S)-3-Hydroxy-p-menth-1-en-6-one

Target:

9alpha,11,12-Trihydroxydrim-7-en-6-one

TN3331

Synonym:

Target: Others

5-Hydroxy-1,7-diphenylhept-6-en-3-one

TN6357

Synonym:

Target:

1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one

TN2514

Synonym:

Target: Others

1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol

TN2513

Synonym:

Target: Others

4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one

TN2994

Synonym:

Target: Others

4|A,6|A-Dihydroxyeudesm-11(13)-en-12,8|A-olide

TN3068

Synonym: 4alpha,6alpha-Dihydroxyeudesm-11(13)-en-12,8beta-olide

Target: Others

6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one

TN3141

Synonym:

Target: Others

1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol

Synonym: (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Target: Others

1,8-Dihydroxy-p-menth-3-en-2-one

TN5870

Synonym: 6-Hydroxy-3-(2-hydroxypropan-2-yl)-6-methylcyclohex-2-en-1-one

Target:

Prosaikogenin F

TN6864

Synonym: (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol

Target: Others

Stevia impurity (13-[(2-O-6-deoxy-Î²-D-glucopyranosyl-3-O-Î²-D-glucopyranosyl-Î²-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid Î²-D-glucopyranosyl ester)

TN6498

Synonym:

Target:

25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside

TN1201

Synonym: (1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside

Target: Others

1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one

TN2512

Synonym:

Target: Others

Dammar-20(21)-en-3,24,25-triol

TN3755

Synonym:

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00827	Tau-D Protein, Human, Recombinant (His)	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPK-00614	NKp46/NCR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-03010	NRG1 beta 1 Protein, Human, Recombinant	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPY-02705	NRG1 beta 1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPY-02600	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-05798	VEGF145 Protein, Human, Recombinant	Human	HEK293 Cells
	VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPY-03128	LAIR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPK-00615	NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-01364	SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01358	SIRP alpha V6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...