ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T14034 | 3CAI | 28755-03-5 | 98% |
|
| 3CAI is a potent and specific AKT1 and AKT2 inhibitor which showed significant inhibition of AKT in an in vitro kinase assay and suppressed expression of AKT dir... | ||||
| T6252 | Ipatasertib | 1001264-89-6 | 98% |
|
| Ipatasertib (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively. | ||||
| T3P2904 | α-Linolenic acid | 463-40-1 | 98% |
|
| Linolenic Acid is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to in... | ||||
| T0228 | Methyl-Hesperidin | 11013-97-1 | 98% |
|
| Methyl Hesperidin, a flavanone glycoside (flavonoid) (C28H34O15), is abundant in citrus fruits. Its aglycone form is called hesperetin. | ||||
| T2S1040 | Jolkinolide B | 37905-08-1 | 98% |
|
| Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can... | ||||
| T4046 | BX517 | 850717-64-5 | 98% |
|
| BX-517 is a potent and selective inhibitor of PDK1. | ||||
| T14072 | A-443654 | 552325-16-3 | 98% |
|
| A-443654 is a pan-Akt inhibitor. It has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM). | ||||
| T4489 | AKT-IN-1 | 1357158-81-6 | 98% |
|
| AZD-26 is an allosteric AKT inhibitor (IC50: 1.04 μM). | ||||
| T15469 | Hematein | 475-25-2 | 98% |
|
| Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway, and increases apoptosis in lung cancer cells. Hematein is an oxidation product of hematoxy... | ||||
| T9831 | MKC-1 | 125313-92-0 | 98% |
|
| MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhib... | ||||
| T5S0168 | Atractylenolide II | 73069-14-4 | 98% |
|
| 1. Atractylenolide II has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK ... | ||||
| T15374 | Ipatasertib dihydrochloride | 1396257-94-5 | 98% |
|
| Ipatasertib dihydrochloride is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively). | ||||
| T4444 | A-674563 HCl (552325-73-2(free base)) | 98% |
|
|
| A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 ... | ||||
| T3132 | SC66 | 871361-88-5 | 98% |
|
| SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h). | ||||
| TN2063 | Physalin B | 23133-56-4 | 98% |
|
| Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammat... | ||||
| T23695 | Akt-I-1,2 | 473382-50-2 | 98% |
|
| Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2. | ||||
| T2895 | Lupeol | 545-47-1 | 98% |
|
| Lupeol is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity. | ||||
| T6303 | CCT128930 | 885499-61-6 | 98% |
|
| CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinas... | ||||
| T0392 | Artemisinin | 63968-64-9 | 98% |
|
| Artemisinin is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organis... | ||||
| T25017 | AKT-I-1 | 473382-39-7 | 98% |
|
| AKT-I-1 is a selective and reversible inhibitor of Akt1. | ||||
