G12C | TargetMol

カタログ番号	製品名	別名	ターゲット
T40286	KRAS G12C inhibitor 19		Ras
	KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in cellular assays, and the family inhibits tumor growth.		Ras
T6556	K-Ras(G12C) inhibitor 9		Raf
	K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).		Raf
T3725	K-Ras(G12C) Inhibitor 6		Raf
	K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.		Raf
T6555	K-Ras(G12C) inhibitor 12		Apoptosis , Raf , Ras
	K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).		Apoptosis , Raf , Ras
T11738	K-Ras G12C-IN-4		Ras
	K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C..		Ras
T40285	KRAS G12C inhibitor 18
	KRAS G12C inhibitor 18 is a potent, orally active compound that inhibits KRAS G12C and exhibits anti-tumor activities.
T77802	KRAS G12C inhibitor 1R
	KRAS G12C inhibitor 1R can be used in studies about Ras.
T11769	KRAS G12C inhibitor 15		Ras
	KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .		Ras
T11768	KRAS G12C inhibitor 14		Ras
	KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].		Ras
T11778	KRas G12C inhibitor 3		Ras
	KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.		Ras
T11780	KRAS G12C inhibitor 5		Ras
			Ras
T11767	KRAS G12C inhibitor 13		Ras
	KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .		Ras
T11779	KRas G12C inhibitor 4		Ras
	KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.		Ras
T11776	KRas G12C inhibitor 1		Ras
	KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.		Ras
T11771	KRAS G12C inhibitor 17		Ras
	KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.		Ras
T11770	KRAS G12C inhibitor 16		Ras
	KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.		Ras
T11777	KRas G12C inhibitor 2		Ras
	KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.		Ras
T11736	K-Ras G12C-IN-2		Others
	K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.		Others
T11735	K-Ras G12C-IN-1		Phosphatase
	K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.		Phosphatase
T11737	K-Ras G12C-IN-3		Others
	Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.		Others
T77805	KRAS G12C mutant protein inhibitor A-1
	KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.
T78651	Glecirasib	JAB-21822,KRAS G12C inhibitor 36	Ras
	Glecirasib (KRAS G12C inhibitor 36) is a potent inhibitor targeting the oncogenic KRAS G12C mutation, a key signaling molecule within the Ras protein family that is crucial for cell growth and development. This compound ...		Ras
T63927	KRAS G12C inhibitor 25
	KRAS G12C inhibitor 25 is an inhibitor of KRAS G12C. KRAS G12C inhibitor 25 inhibits the SOS1-assisted GDP/GTP exchange activity of KRAS-G12C mutants with an IC50 value of 0.48 nM.
T62566	KRAS G12C inhibitor 53
	KRAS G12C inhibitor 53 (Compound 1) is a KRAS G12C inhibitor.
T64095	KRAS G12C inhibitor 42
	KRAS G12C inhibitor 42 is a potent inhibitor of KRAS G12C. KRAS G12C inhibitor 42 has shown potential for the investigation of KRAS G12C-mediated cancers.
T63502	KRAS G12C inhibitor 31
	KRAS G12C inhibitor 31 is an inhibitor of KRAS G12C that can be used to study cancer.
T72335	KRAS G12C inhibitor 32		Ras
	KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1].		Ras
T63863	KRAS G12C inhibitor 47
	KRAS G12C inhibitor 47 is a potent inhibitor of KRAS G12C (IC50: 0.172 μM). KRAS G12C inhibitor 47 exhibits p-ERK inhibition in MIA PaCA-2 cells, A549 cells with IC50 values of 0.046 μM and 69.8 μM respectively. KRAS G12...
T64093	KRAS G12C inhibitor 44
	KRAS G12C inhibitor 44 is a potent, orally active KRAS G12C inhibitor. KRAS G12C inhibitor 44 exhibits anti-proliferative effects in MIA PaCA-2 (IC50: 0.016 μM), H358 cells (IC50: 0.028 μM). inhibitor 44 has anti-tumour ...
T72344	KRAS G12C inhibitor 41
	KRAS G12C Inhibitor 41 is a potent agent targeting the KRAS G12C mutation within the Ras family of proteins, which are crucial for intracellular signaling related to growth and development. This compound holds significan...
T72338	KRAS G12C inhibitor 35
	KRAS G12C Inhibitor 35 is a potent suppressor of KRAS G12C, targeting a crucial member of the Ras protein family which significantly impacts cellular growth and development. This compound holds promise for investigating ...
T72346	KRAS G12C inhibitor 20
	KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.
T72336	KRAS G12C inhibitor 45
	KRAS G12C inhibitor 45 is a potent KRAS G12C inhibitor .
T64142	KRAS G12C inhibitor 46
	KRAS G12C inhibitor 46 is a potent inhibitor of KRAS G12C.
T63807	KRAS G12C inhibitor 33
	KRAS G12C inhibitor 33 is a KRAS G12C inhibitor that can be used to study cancer.
T63501	KRAS G12C inhibitor 30
	KRAS G12C inhibitor 30 is an inhibitor of KRAS G12C and can be used to study cancer.
T64033	KRAS G12C inhibitor 34
	KRAS G12C inhibitor 34 is an inhibitor of KRAS G12C that can be used to study cancer research.
T72343	KRAS G12C inhibitor 40
	KRAS G12C inhibitor 40, a potent suppressor of the KRAS G12C, targets the Ras family of intracellular signaling proteins crucial for growth and development. This compound holds significant potential for researching cance...
T72356	KRAS G12C inhibitor 56
	KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.
T63926	KRAS G12C inhibitor 22
	KRAS G12C inhibitor 22 is a KRAS G12C inhibitor.
T64115	KRAS G12C inhibitor 51
	KRAS G12C inhibitor 51 is a KRAS G12C inhibitor.
T64097	KRAS G12C inhibitor 21
	KRAS G12C inhibitor 21 is a KRAS G12C inhibitor.
T63891	KRAS G12C inhibitor 50
	KRAS G12C inhibitor 50 is a KRAS G12C inhibitor (IC50: 46.7 nM).
T72342	KRAS G12C inhibitor 39
	KRAS G12C Inhibitor 39, a potent antagonist, specifically targets the KRAS G12C mutation, a prime focus in pharmaceutical cancer research. This compound shows promise for investigating KRAS G12C-mediated cancer.
T62785	KRAS G12C inhibitor 29
	KRAS G12C inhibitor 29 is an inhibitor of KRAS G12C and can be used to study cancer.
T72347	KRAS G12C inhibitor 24
	KRAS G12C Inhibitor 24 is a potent inhibitor that effectively disrupts the interaction between KRAS G12C and SOS1, achieving an inhibitory concentration (IC 50) of less than 50 nM.
T64039	KRAS G12C inhibitor 49
	KRAS G12C inhibitor 49 is an orally active KRAS G12C inhibitor that exhibits antitumour effects.
T79057	KRAS G12C inhibitor 58		Ras
	KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].		Ras
T72340	KRAS G12C inhibitor 37
	KRAS G12C Inhibitor 37, a potent inhibitor of KRAS G12C, targets the Ras family of proteins, crucial for intracellular signaling related to growth and development. This compound holds potential for research into cancers ...
T72334	KRAS G12C inhibitor 28
	KRAS G12C Inhibitor 28 is a compound that effectively inhibits the KRAS G12C mutation, exhibiting potent antitumor effects with an inhibitory concentration (IC50) of 57 nanomoles (nM).

Compounds

KRAS G12C inhibitor 19

T40286

Synonym:

Target: Ras

K-Ras(G12C) inhibitor 9

T6556

Synonym:

Target: Raf

K-Ras(G12C) Inhibitor 6

T3725

Synonym:

Target: Raf

K-Ras(G12C) inhibitor 12

T6555

Synonym:

Target: Apoptosis, Raf, Ras

KRAS G12C inhibitor 18

T40285

Synonym:

Target:

KRAS G12C inhibitor 1R

T77802

Synonym:

Target:

KRAS G12C inhibitor 15

T11769

Synonym:

Target: Ras

KRAS G12C inhibitor 14

T11768

Synonym:

Target: Ras

KRas G12C inhibitor 3

T11778

Synonym:

Target: Ras

KRAS G12C inhibitor 5

T11780

Synonym:

Target: Ras

KRAS G12C inhibitor 13

T11767

Synonym:

Target: Ras

KRas G12C inhibitor 4

T11779

Synonym:

Target: Ras

KRas G12C inhibitor 1

T11776

Synonym:

Target: Ras

KRAS G12C inhibitor 17

T11771

Synonym:

Target: Ras

KRAS G12C inhibitor 16

T11770

Synonym:

Target: Ras

KRas G12C inhibitor 2

KRAS G12C mutant protein inhibitor A-1

Synonym: JAB-21822,KRAS G12C inhibitor 36

Target: Ras

KRAS G12C inhibitor 25

T63927

Synonym:

Target:

KRAS G12C inhibitor 53

T62566

Synonym:

Target:

KRAS G12C inhibitor 42

T64095

Synonym:

Target:

KRAS G12C inhibitor 31

T63502

Synonym:

Target:

KRAS G12C inhibitor 32

T72335

Synonym:

Target: Ras

KRAS G12C inhibitor 47

T63863

Synonym:

Target:

KRAS G12C inhibitor 44

T64093

Synonym:

Target:

KRAS G12C inhibitor 41

T72344

Synonym:

Target:

KRAS G12C inhibitor 35

T72338

Synonym:

Target:

KRAS G12C inhibitor 20

T72346

Synonym:

Target:

KRAS G12C inhibitor 45

T72336

Synonym:

Target:

KRAS G12C inhibitor 46

T64142

Synonym:

Target:

KRAS G12C inhibitor 33

T63807

Synonym:

Target:

KRAS G12C inhibitor 30

T63501

Synonym:

Target:

KRAS G12C inhibitor 34

T64033

Synonym:

Target:

KRAS G12C inhibitor 40

T72343

Synonym:

Target:

KRAS G12C inhibitor 56

T72356

Synonym:

Target:

KRAS G12C inhibitor 22

T63926

Synonym:

Target:

KRAS G12C inhibitor 51

T64115

Synonym:

Target:

KRAS G12C inhibitor 21

T64097

Synonym:

Target:

KRAS G12C inhibitor 50

T63891

Synonym:

Target:

KRAS G12C inhibitor 39

T72342

Synonym:

Target:

KRAS G12C inhibitor 29

T62785

Synonym:

Target:

KRAS G12C inhibitor 24

T72347

Synonym:

Target:

KRAS G12C inhibitor 49

T64039

Synonym:

Target:

KRAS G12C inhibitor 58

T79057

Synonym:

Target: Ras

KRAS G12C inhibitor 37

T72340

Synonym:

Target:

KRAS G12C inhibitor 28

T72334

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPJ-00510	KRAS Protein, Human, Recombinant (G12C, His)	Human	E. coli
	KRAS Protein, Human, Recombinant (G12C, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 KDa and the accession number is AAH13572.1.
TMPK-01463	HLA-A11:01&B2M&KRAS G12C* (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01433	HLA-A11:01&B2M&KRAS G12C* (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01462	HLA-A11:01&B2M&KRAS G12C* (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...