Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
説明 | K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). |
In vitro | K-Ras(G12C) inhibitor 12 belongs to a series of small molecules, which irreversibly bind to a common oncogenic mutant K-Ras(G12C) and blocks K-Ras(G12C) interactions. Some of them decrease viability and increase apoptosis of G12C-containing cancer cell lines. [1] |
分子量 | 449.67 |
分子式 | C15H17ClIN3O3 |
CAS No. | 1469337-95-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 26 mg/mL (57.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
K-Ras(G12C) inhibitor 12 1469337-95-8 Apoptosis GPCR/G Protein MAPK Raf Ras K-Ras(G-12C) inhibitor 12 inhibit Inhibitor KRas(G12C) inhibitor 12 K Ras(G12C) inhibitor 12 inhibitor