GTP-dependent | TargetMol

カタログ番号	製品名	別名	ターゲット
T71857	GTP-14564		FLT , Tyrosine Kinases
	GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentratio...		FLT , Tyrosine Kinases
T68873	Cornigerine
	Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum that inhibited tubulin polymerization both with and without microtubule-associated proteins, inhibited the binding of radiolabeled co...
T74356	PROTAC SOS1 degrader-2
	PROTAC SOS1 degrader-2, a potent degrader of PROTAC SOS1, effectively reduces the expression of pERK and RAS-GTP in a dose-dependent manner. It significantly inhibits tumor growth in vivo [1].
T83820	TNP-GTP sodium	TNP-Guanosine 5'-triphosphate
	TNP-GTP, a fluorescent derivative of guanosine 5'-triphosphate (GTP), essential for protein synthesis and gluconeogenesis, exhibits an emission peak at 552 nm when excited at 410 nm in water. Its fluorescence intensity i...
T22631	Dolastatin 10 trifluoroacetate		Others
	Dolastatin 10 trifluoroacetate is a potent antimitotic polypeptide isolated from a marine animal and is developed as a potential antitumor agent. Dolastatin 10 is found to have an activity to inhibit tubulin polymerizati...		Others
T81754	MP6	Myr-FEEERA-OH	Integrin
	mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function. Additionally, mP6 impedes the GTPase activity of Rac1, Rap1, an...		Integrin

Compounds

GTP-14564

T71857

Synonym:

Target: FLT, Tyrosine Kinases

PROTAC SOS1 degrader-2

Synonym: TNP-Guanosine 5'-triphosphate

Target:

Dolastatin 10 trifluoroacetate

Synonym: Myr-FEEERA-OH

Target: Integrin

カタログ番号	製品名	別名	ターゲット
T8211	(±)-Decursinol	3',4'-dihydro-3'-hydroxy-Xanthyletin	Others , Antibacterial
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPH-00020	Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His)	Acinetobacter baumannii	P. pastoris (Yeast)
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
TMPH-03742	EEF1A1 Protein, Cricetulus griseus, Recombinant (His)	Chinese hamster	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPH-03194	GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc)	Pyrococcus horikoshii	E. coli
	Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also utilize GTP, CTP, UTP, ADP or pyrophosphate as phosphate donor. GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc) is...
TMPH-01287	TUFM Protein, Human, Recombinant (His)	Human	E. coli
	Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochon...
TMPY-01187	Rac1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re...
TMPH-01284	EEF1A1 Protein, Human, Recombinant	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPH-01283	EEF1A1 Protein, Human, Recombinant (His)	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPH-00732	RtcB Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici...
TMPY-02129	Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutamina...
TMPH-01420	SAR1A Protein, Human, Recombinant (GST)	Human	E. coli
	Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent a...
TMPH-01286	EEF2 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form...
TMPH-01524	KPNA1 Protein, Human, Recombinant (His)	Human	E. coli
	Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate com...
TMPH-00207	PTX S1 Protein, Bordetella pertussis, Recombinant (His)	Bordetella pertussis	P. pastoris (Yeast)
	S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the a...
TMPY-04484	ACK1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...