ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T9473 | 4SC-203 | 895533-09-2 | 98% |
|
| 4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated f... | ||||
| T6115 | Fostamatinib | 901119-35-5 | 98% |
|
| Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn. | ||||
| T2051 | SKLB4771 | 1370256-78-2 | 98% |
|
| FLT3-IN-1 is a novel potent and selective Flt3 inhibitor. | ||||
| T4261 | BPR1J-097 hydrochloride (1327167-19-0(free base)) | T4261 | 98% |
|
| BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo. | ||||
| T1995 | Fedratinib | 936091-26-8 | 98% |
|
| Fedratinib (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3. | ||||
| T2066 | Quizartinib | 950769-58-1 | 98% |
|
| Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. | ||||
| T2272 | BPR1J-097 | 1327167-19-0 | 98% |
|
| BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM). | ||||
| T14072 | A-443654 | 552325-16-3 | 98% |
|
| A-443654 is a pan-Akt inhibitor. It has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM). | ||||
| T6028 | PF 477736 | 952021-60-2 | 98% |
|
| PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes. | ||||
| T4227 | SB1317 hydrochloride (1204918-72-8(free base)) | T4227 | 98% |
|
| SB1317 is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM). | ||||
| T6982 | SGI-7079 | 1239875-86-5 | 98% |
|
| SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR... | ||||
| T21503 | (E/Z)-Zotiraciclib | 937270-47-8 | 98% |
|
| (E/Z)-Zotiraciclib inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively. | ||||
| T6S0033 | Crotonoside | 1818-71-9 | 98% |
|
| 1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of th... | ||||
| TQ0235 | AC710 | 1351522-04-7 | 98% |
|
| AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ). | ||||
| T13564 | AZ7550 | 1421373-99-0 | 98% |
|
| AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM). | ||||
| T6331 | Allitinib tosylate | 1050500-29-2 | 98% |
|
| AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively. | ||||
| T2116 | AEE788 | 497839-62-0 | 98% |
|
| AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors. | ||||
| T7104 | Dovitinib lactate | 692737-80-7 | 98% |
|
| Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM). | ||||
| T8317 | 5'-Fluoroindirubinoxime | 861214-33-7 | 98% |
|
| 5'-Fluoroindirubinoxime is a potent FLT3 inhibitor( IC50 : 15 nM). | ||||
| T3621 | Brigatinib | 1197953-54-0 | 98% |
|
| Brigatinib is a highly potent and selective ALK inhibitor. | ||||
