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Search Results for " HAE "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP1401	HAE	His-Ala-Glu	Others
	HAE (His-Ala-Glu) consists of histidine, alanine and glutamate.		Others
TP1401L	HAE acetate(64111-99-5 free base)		Others
	HAE acetate is a 3-amino acid peptide composed of histidine, alanine and glutamate		Others
TP1419L	HAEGTFT acetate(926018-95-3 free base)		Glucagon Receptor
	HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.		Glucagon Receptor
TP1381L	HAEGT TFA(852155-81-8 free base)		Others
	HAEGT TFA is the first N-terminal 1-5 residues of GLP-1 peptide.		Others
TP1382L	HAEGTFTSDVS acetate	HAEGTFTSDVS acetate(864915-61-7 free base)	Glucagon Receptor
	HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.		Glucagon Receptor
TP1388	HAEGTFTSDVSSYLE		Others
	HAEGTFTSDVSSYLE is a peptide. GLP-I analog contains the sequence.		Others
T129448	19-O-Acetylchaetoglobosin D
	19-O-Acetylchaetoglobosin D is a useful organic compound for research related to life sciences and the catalog number is T129448.
TP1419	HAEGTFT
	HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.
T11534L	Haemanthamine hydrochloride (466-75-1 free base)	Haemanthamine hydrochloride	Others
	Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-ap...		Others
T78602	Chaetoglobosin C
	Chaetoglobosin C (Compound 4), an anthraquinone-chromone derivative of Chaetomium globosum KMITL-N0802, exhibits anti-tuberculosis activity [1].
TP1382	HAEGTFTSDVS
	HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
TP1381	HAEGT
	HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.
T70554	Chaetomellic acid A
	Chaetomellic acid A is a potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and I...
T71469	Chaetochromin D
	Chaetochromin D also known as 4548-G05, is an orally active, small-molecule, selective agonist of the insulin receptor.
T125487	Chaetopenoid B
	Chaetopenoid B is a useful organic compound for research related to life sciences. The catalog number is T125487 and the CAS number is 1893386-00-9.
T71468	Chaetochromin C
	Chaetochromin C also known as 4548-G05, is an orally active, small-molecule, selective agonist of the insulin receptor.
T130184	Sphaerindicin
	Sphaerindicin is a useful organic compound for research related to life sciences and the catalog number is T130184.
T124574	Cephaeline dihydrobromide
	Cephaeline dihydrobromide is a useful organic compound for research related to life sciences and the catalog number is T124574.
TP1452	HAEGTFTSD
	HAEGTFTSD is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food.
T125488	Chaetopenoid A
	Chaetopenoid A is a useful organic compound for research related to life sciences. The catalog number is T125488 and the CAS number is 1893385-99-3.
T34691	Sphaeropsidin A	LL S491beta,LLS491beta,LL-S491beta,Sphaeropsidin A, (+)-,Antibiotic LL-S491beta
	Sphaeropsidin A is the main phytotoxin produced by Diplodia cupressi.
T34692	Sphaeropsidin B	LL S491gamma,LLS491gamma,Antibiotic LL-S491gamma,LL-S491gamma,Pinowiltin
	Sphaeropsidin B is a fungal phytotoxin.
T125786	Sphaerobioside
	Sphaerobioside is a useful organic compound for research related to life sciences. The catalog number is T125786 and the CAS number is 14988-20-6.
T30869	Chaetominine	NSC 746369,NSC-746369,NSC746369
	Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.
TP1452L1	HAEGTFTSD acetate(926018-45-3 free base)		Glucagon Receptor
	HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food.		Glucagon Receptor
T70161	Berotralstat HCl
	Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated wi...
T35869	Berotralstat
	Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks...
T74467	Remdesivir de(ethylbutyl 2-aminopropanoate)
	Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human air...

Compounds

HAE

TP1401

Synonym: His-Ala-Glu

Target: Others

HAE acetate(64111-99-5 free base)

TP1401L

Synonym:

Target: Others

HAEGTFT acetate(926018-95-3 free base)

TP1419L

Synonym:

Target: Glucagon Receptor

HAEGT TFA(852155-81-8 free base)

TP1381L

Synonym:

Target: Others

HAEGTFTSDVS acetate

TP1382L

Synonym: HAEGTFTSDVS acetate(864915-61-7 free base)

Target: Glucagon Receptor

19-O-Acetylchaetoglobosin D

Haemanthamine hydrochloride (466-75-1 free base)

T11534L

Synonym: Haemanthamine hydrochloride

HAEGT

Cephaeline dihydrobromide

Synonym: LL S491beta,LLS491beta,LL-S491beta,Sphaeropsidin A, (+)-,Antibiotic LL-S491beta

Target:

Sphaeropsidin B

T34692

Synonym: LL S491gamma,LLS491gamma,Antibiotic LL-S491gamma,LL-S491gamma,Pinowiltin

Synonym: NSC 746369,NSC-746369,NSC746369

Target:

HAEGTFTSD acetate(926018-45-3 free base)

TP1452L1

Synonym:

Target: Glucagon Receptor

Remdesivir de(ethylbutyl 2-aminopropanoate)

T74467

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
TN6717	Chaetoglobosin Vb		Others
	chaetoglobosin Vb is a new cytochalasan alkaloid isolated from endophytic Chaetomium globosum		Others
TN1480	Cephaeline		Virus Protease , Influenza Virus , HIF
	Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.		Virus Protease , Influenza Virus , HIF
T6803	Chaetocin		Histone Methyltransferase , Antibacterial , Antibiotic
	Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.		Histone Methyltransferase , Antibacterial , Antibiotic
T3S1852	Cephaeline hydrochloride		Others , Virus Protease , Influenza Virus
	Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.		Others , Virus Protease , Influenza Virus
T75470	Phaeosphaone D
	Phaeosphaone D, a thiodiketopiperazine alkaloid isolated from the endophytic fungus Phaeosphaeria fuckelii, exhibits inhibitory activity against mushroom tyrosinase, with an IC50 value of 33.2 μM [1].
T81498	Phaeocaulisin E
	Phaeocaulisin E (Compound 5), a guaiane-type sesquiterpene, inhibits LPS-induced NO production in RAW 264.7 macrophages, exhibiting an IC50 value of 10.3 µM [1].
T13608	Chaetoglobosin A		Others
	Chaetoglobosin A, the active compound extracted of Penicillium aquamarinium, is a member of the cytochalasan family. It preferentially induces apoptosis.		Others
TQ0109	Cephaeline dihydrochloride	(-)-Cephaeline dihydrochloride,NSC 32944	P450
	(-)-Cephaeline (dihydrochloride) is an enantiomer of Cephaeline. Cephaeline is a selective CYP2D6 inhibitor (IC50: 121 μM).		P450
T75475	Chaetosemin J
	Chaetosemin J, a metabolite with antifungal properties, effectively inhibits the growth of plant pathogenic fungi including Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, demonstrati...
T75488	Leptosphaerodione
	Leptosphaerodione, a compound derived from the Remotididymella sp. fungus, functions as a potent inhibitor of the ubiquitin-proteasome system (UPS) and demonstrates cytotoxic effects in HeLa cells with an IC50 value of 3...
T75453	11-epi-Chaetomugilin I
	11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemi...
TN3597	Carmichaenine B		Others
	Carmichaenine B is a natiral product from Aconitum carmichaeli.		Others
TN6716	Chaetoglobosin Fex		Immunology/Inflammation related
	Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages.		Immunology/Inflammation related
TN3596	Carmichaenine A		Others
	Carmichaenine A is a natiral product from Aconitum carmichaeli.		Others
T73813	Haemanthamine hydrochloride
	Haemanthamine hydrochloride, a crinine-type alkaloid derived from Amaryllidaceae plants, exhibits potent anticancer properties. It acts by targeting ribosomes, thereby inhibiting protein biosynthesis during the translati...
TN3599	Carmichaenine D		Others
	Carmichaenine D is a natiral product from Aconitum carmichaeli.		Others
TN3598	Carmichaenine C		Others
	Carmichaenine C is a natiral product from Aconitum carmichaeli.		Others
TN3600	Carmichaenine E		Others
	Carmichaenine E is a natiral product from Aconitum carmichaeli.		Others
T68746	Chaetochromin
	Chaetochromin also known as 4548-G05 and NSC 345647, is an orally active, small-molecule, selective agonist of the insulin receptor. It has potent and long-lasting antidiabetic activity in vivo in mice.
T35609	19-O-Acetylchaetoglobosin A
	19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used a...
T11534	Haemanthamine		Others
			Others

天然物製品

Target: Virus Protease, Influenza Virus, HIF

Chaetocin

T6803

Synonym:

Target: Histone Methyltransferase, Antibacterial, Antibiotic

Cephaeline hydrochloride

T3S1852

Synonym:

Target: Others, Virus Protease, Influenza Virus

Cephaeline dihydrochloride

TQ0109

Synonym: (-)-Cephaeline dihydrochloride,NSC 32944

11-epi-Chaetomugilin I

Target: Immunology/Inflammation related

Haemanthamine hydrochloride

19-O-Acetylchaetoglobosin A

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01183	C1 inhibitor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C1 inhibitor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is E9KL26.
TMPH-00360	DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant	Cenarchaeum symbiosum	E. coli
	Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicativ...
TMPH-03653	RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His)	Ustilago sphaerogena	E. coli
	N/A. RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 26.4 kDa and the accession number is P00654.
TMPH-03585	Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)	Staphylococcus haemolyticus	E. coli
	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Dihydropteroate syn...
TMPH-00782	OMP P5 Protein, Haemophilus influenzae, Recombinant (His & Myc & SUMO)	Haemophilus influenzae	E. coli
	Acts as a fimbriae subunit, allowing adhesion to host cells.; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows...
TMPH-00781	IGA1 protease Protein, Haemophilus influenzae, Recombinant (His & Myc)	Haemophilus influenzae	E. coli
	Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments. IGA1 protease Protein, Haemophilus influenzae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-...
TMPH-02397	MIP Protein, Legionella longbeachae, Recombinant (His & Myc)	Legionella longbeachae	E. coli
	Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.
TMPH-00783	YafQ Protein, Haemophilus influenzae, Recombinant (His & Myc)	Haemophilus influenzae	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB. YafQ Protein, Haemophilus influenzae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag...