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Virus Protease

Virus protease or 3C protease are virus cysteine proteases which have essential role in viral replication. The protease cleaves the precursor viral polyprotein to produce functional proteins and enzymes.Virus proteases are attractive target for therapeutic agents for treatment of diseases caused by the common cold virus.Viral protease - a Cys protease fold is similar to that of trypsin-like serine proteases. The active site triad contains Cys147, His40 and Glu71 (PDB entry 1cqq).
Cat. No. 製品名 CAS No. Purity Chemical Structure
T8328 STING agonist-1 702662-50-8 98%
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
T13397 ZINC03129319 1777807-64-3 98%
ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease.
T11281L FGI-106 tetrahydrochloride 1149348-10-6 98%
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, ...
T77423 Lirilumab 1000676-41-4 98%
Lirilumab
Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical c...
T76856 Andecaliximab 1518996-49-0 98%
Andecaliximab
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model o...
T76690 Mavrilimumab 1085337-57-0 98%
Mavrilimumab
Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating...
TN6508 Trachelogenin 34209-69-3 98%
Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to aff...
T1954 SRPIN340 218156-96-8 98%
SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
T1776L Plerixafor octahydrochloride 155148-31-5
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting ...
T6605 NH125 278603-08-0
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
T18928 Brilliant Black BN 2519-30-4
Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV7...
T2A2498 L-Lysine 56-87-1 100%
L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats...
T1776 Plerixafor 110078-46-1 100%
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
T0005 Aspirin 50-78-2 100%
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Asp...
T5666 Dipotassium glycyrrhizinate 68797-35-3 89.63%
Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.
T16913 Sotirimod 227318-75-4 95.87%
Sotirimod(R850) is a novel immunomodulator with antitumor and antiviral activity for the study of actinic keratoses.
T8903 Retro-2 1201652-50-7 96.08%
Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retro...
T73097 SID-852843 909859-19-4 97.19%
SID-852843 is a WNV NS2B-NS3 protease inhibitor with an IC50 value of 0.105 μM for WNV NS2B-NS3 protease.SID-852843 can be used for the study of viral infections...
T6327 Tubacin 537049-40-4 97.62%
Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.
T3S1852 Cephaeline hydrochloride 3738-70-3 97.81%
Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.
STING agonist-1
T8328
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
ZINC03129319
T13397
ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease.
FGI-106 tetrahydrochloride
T11281L
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, ...
Lirilumab
T77423
Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical c...
Andecaliximab
T76856
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model o...
Mavrilimumab
T76690
Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating...
Trachelogenin
TN6508
Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to aff...
SRPIN340
T1954
SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
Plerixafor octahydrochloride
T1776L
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting ...
NH125
T6605
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
Brilliant Black BN
T18928
Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV7...
L-Lysine
T2A2498
L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats...
Plerixafor
T1776
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
Aspirin
T0005
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Asp...
Dipotassium glycyrrhizinate
T5666
Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.
Sotirimod
T16913
Sotirimod(R850) is a novel immunomodulator with antitumor and antiviral activity for the study of actinic keratoses.
Retro-2
T8903
Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retro...
SID-852843
T73097
SID-852843 is a WNV NS2B-NS3 protease inhibitor with an IC50 value of 0.105 μM for WNV NS2B-NS3 protease.SID-852843 can be used for the study of viral infections...
Tubacin
T6327
Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.
Cephaeline hydrochloride
T3S1852
Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.
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