|
T7147 |
Valbenazine
|
NBI-98854 |
Monoamine Transporter
|
|
Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia. |
|
T1110 |
Meclizine dihydrochloride
|
Meclozine dihydrochloride,NSC28728,Meclizine 2HCl |
Apoptosis
,
Histamine Receptor
|
|
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. |
|
T8081 |
LC3-mHTT-IN-AN1
|
|
Others
,
Autophagy
,
ATTECs
|
|
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner... |
|
T7352 |
Pridopidine
|
ACR16,ASP2314,FR310826 |
Dopamine Receptor
|
|
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model. |
|
T74247 |
TPE-MI
|
|
|
|
Tetraphenylethene maleimide (TPE-MI) serves as a thiol probe to assess unfolded protein levels and proteostasis within cells. It is particularly effective in identifying proteostasis imbalances in both induced pluripoten... |
