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Search Results for " LKB1 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T5093	Pim1/AKK1-IN-1	LKB1/AAK1 dual inhibitor,MDK-2275	Pim , Hippo pathway
	Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.		Pim , Hippo pathway
T13173	TMPA		Others , AMPK
	TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.		Others , AMPK

Compounds

Pim1/AKK1-IN-1

T5093

Synonym: LKB1/AAK1 dual inhibitor,MDK-2275

Target: Pim, Hippo pathway

カタログ番号	製品名	別名	ターゲット
T3904	Gomisin J		Calcium Channel , AMPK
	Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...		Calcium Channel , AMPK
T2854	Phillyrin	Forsythin	P450 , Influenza Virus , AMPK
	Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activ...		P450 , Influenza Virus , AMPK
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

天然物製品

Gomisin J

T3904

Synonym:

Target: Calcium Channel, AMPK

Phillyrin

T2854

Synonym: Forsythin

Target: P450, Influenza Virus, AMPK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00766	KLKB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...
TMPH-03351	KLKB1 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role ...
TMPH-03352	KLKB1 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role ...
TMPK-00525	KLKB1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...
TMPK-00857	KLKB1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...