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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2399 | Bortezomib | Radiciol,NSC 681239,MG 341,DPBA,Brotezamide,LDP 341 | Apoptosis , NF-κB , Proteasome , Autophagy |
Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis. | |||
T37201 | CAY10787 | ||
CAY10787 is an oxysterol and a negative allosteric modulator of GABAAreceptors.1,2It reduces GABA-induced currents in HEK cells expressing α1β1γ2or α4β3γ2subunit-containing GABAAreceptors (IC50s = 1.5 and 1 μM, respectiv... | |||
T37847 | Zonisamide-13C2,15N | Zonisamide-13C2,15N | |
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels ... | |||
T36400 | Para-amino-Blebbistatin | ||
para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of n... |