|
T4367 |
Mycro 3
|
Mycro-3 |
c-Myc
,
Autophagy
|
|
Mycro 3 is potent and selective for c-Myc in whole cell assays. |
|
T60019 |
VPC-70063
|
Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- |
Apoptosis
,
PARP
,
c-Myc
|
|
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C do... |
|
T9093 |
NY2267
|
Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester |
c-Myc
|
|
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester) is a disruptor of Myc-Max interaction, with an IC50 of 36... |
|
T3686 |
10074-G5
|
|
c-Myc
,
Autophagy
|
|
10074-G5 is an inhibitor of c-Myc-Max dimerization. |
|
T3048 |
10058-F4
|
c-Myc Inhibitor |
c-Myc
,
Autophagy
|
|
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis. |
|
T12133 |
MYCi975
|
NUCC-0200975 |
c-Myc
|
|
MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC. |
|
T24513 |
MYRA-A
|
NSC-339585,NSC 339585,NSC339585 |
|
|
MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction. |
|
T78986 |
MDEG-541
|
|
c-Myc
|
|
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1]. |
|
T69464 |
Mycro2
|
|
|
|
Mycro2 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max. |
|
T69465 |
Mycro1
|
|
|
|
Mycro1 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max. |
|
T9731 |
VPC-70619
|
|
|
|
VPC-70619 is a potent, orally active and selective N-Myc inhibitor that inhibits cancer cell growth by blocking the binding of N-Myc-Max compounds to the E-box of DNA. It can be efficiently absorbed and utilized by the b... |
