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PARP

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T6892 Niraparib tosylate 1038915-73-9 98%
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
TN2883 3',4'-Dimethoxyflavone 4143-62-8 98%
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
T6578 ME0328 1445251-22-8 98%
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
T10990 Dehydrocorydaline chloride 10605-03-5 98%
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
T4472 NMS-P118 1262417-51-5 98%
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
T2105 Veliparib dihydrochloride 912445-05-7 98%
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It i...
T1807 JW 55 664993-53-7 98%
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2)...
T9756 AZD-9574 2756333-39-6 98%
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and...
T6197 PJ34 344458-19-1 98%
PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
T12365 PARP/PI3K-IN-1 2337386-47-5 98%
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antipr...
T9165 AZD5305 2589531-76-8 98%
AZD5305 is a potent, selective and oral active PARP inhibitor.
T73496 OUL232 943119-42-4 98%
OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.
T72553 ARTD10/PARP10-IN-1 1708103-76-7 98%
ARTD10/PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly ADP-ribose polymerase-1 (ART...
TN1651 Furanodiene 19912-61-9 98%
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T3168 MN-64 92831-11-3 98%
MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
T6253 Talazoparib 1207456-01-6 98%
Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
T78182 PARP-1-IN-4 684234-56-8 98%
PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.
T78157 PARP-1-IN-3 2976342-33-1 98%
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inf...
T50098 TIQ-A 420849-22-5
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excess...
T50044 5-AIQ 93117-08-9 95.00%
5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.
Niraparib tosylate
T6892
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
3',4'-Dimethoxyflavone
TN2883
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
ME0328
T6578
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
Dehydrocorydaline chloride
T10990
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
NMS-P118
T4472
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
Veliparib dihydrochloride
T2105
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It i...
JW 55
T1807
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2)...
AZD-9574
T9756
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and...
PJ34
T6197
PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
PARP/PI3K-IN-1
T12365
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antipr...
AZD5305
T9165
AZD5305 is a potent, selective and oral active PARP inhibitor.
OUL232
T73496
OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.
ARTD10/PARP10-IN-1
T72553
ARTD10/PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly ADP-ribose polymerase-1 (ART...
Furanodiene
TN1651
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
MN-64
T3168
MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
Talazoparib
T6253
Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
PARP-1-IN-4
T78182
PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.
PARP-1-IN-3
T78157
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inf...
TIQ-A
T50098
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excess...
5-AIQ
T50044
5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.
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