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Search Results for " NKCC "

ターゲット

Na-K-Cl cotransporter

3

阻害剤

1

天然化合物

カタログ番号	製品名	別名	ターゲット
T10441	Azosemide		Na-K-Cl cotransporter
	Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B).		Na-K-Cl cotransporter
T35336	Furosemide sodium	Frusemide Sodium,Lasix	Na-K-Cl cotransporter
	Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity ...		Na-K-Cl cotransporter
T61713	Bumetanide sodium
	Bumetanide sodium is a potent loop diuretic that acts as a blocker for the sodium-potassium-chloride cotransporter (NKCC). It selectively inhibits NKCC1 and NKCC2, with IC50 values of 0.68 μM and 4.0 μM for hNKCC1A and h...

Compounds

Target: Na-K-Cl cotransporter

Furosemide sodium

Synonym: Frusemide Sodium,Lasix

Target: Na-K-Cl cotransporter

Bumetanide sodium

カタログ番号	製品名	別名	ターゲット
T3604	Sodium dichloroacetate	Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)	Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
	Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...		Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK

天然物製品

Sodium dichloroacetate

Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

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