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Search Results for " Penicillium "

阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T125940	Penicilliumin A
	Penicilliumin A is a useful organic compound for research related to life sciences. The catalog number is T125940 and the CAS number is 1393131-81-1.
T29345	2-Ethyl-5-methylphenol		Others
	2-Ethyl-5-methylphenol is an alkylphenol that can be isolated or identified from Penicillium aurantiogriseum, P. verrucosum and P. viridicatum.		Others
T124797	Ochratoxin B		Endogenous Metabolite
	Ochratoxin B is produced by a variety of Aspergillus and Penicillium species and is an analog of the mycotoxin Ochratoxin A, which can contaminate agricultural products.		Endogenous Metabolite
T27300	Olorofim	Olorofim,F901318,F-901318
	Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pa...
T34190	Puberuline	Fructigenine A,Rugulosuvine-B,Fructigenine-A,Rugulosuvine B,Puberulin
	Puberuline is a diketopiperazine alkaloid isolated from Penicillium piscarium.
T80312	PAF26
	PAF26 is an antimicrobial peptide that exhibits efficacy against phytopathogenic fungi, including Penicillium digitatum, Penicillium italicum, and Botrytis cinerea [1].
T32982	Luteoskyrin	Flavomycelin
	Luteoskyrin is a hepatotoxic and hepatocarcinogenic bisdihydroanthraquinone produced by Penicillium islandicum Sopp.
T34444	Rubroskyrin
	Rubroskyrin is a modified bis-anthraquinone pigment that comes from Penicillium islandicum Sopp.
T32262	Janthitrem G
	Janthitrem G is a type of naphthopyran. Janthitrem G is obtained from Penicillium janthinellum. Tremorgenic mycotoxi.
T32259	Janthitrem C
	Janthitrem c is a type of naphthopyran. Janthitrem C is obtained form Penicillium janthinellum. Tremorgenic mycotoxin.
T38315	Penigequinolone A
	Penigequinolone A is produced by Penicillium sp., No. 410 and acts as a pollen growth inhibitor.
T33551	N(alpha)-Acetylfusarinines	Nalpha-Acetylfusarinines
	N(alpha)-Acetylfusarinines is a group of naturally occurring hydroxamic acids produced by unidentified species of Penicillium when grown on iron-deficient media.
T32258	Janthitrem B
	Janthitrem B is a trematoxin produced by certain isolates of Penicillium violaceum.
T34717	Stevastelin B3	NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3
	Stevastelin B3 is a depsipeptide isolated from Penicillium.
T32260	Janthitrem E
	Janthitrem E is a type of naphthopyran. Janthitrem E is obtained from Penicillium janthinellum. Tremorgenic mycotoxi.
T34447	Rugulin
	Rugulin is a minor metabolite from Penicillium rugulosum and a naturally occurring bisanthraquinone.
T31761	Fellutamide A
	Fellutamide A as a tripeptide derivative from Penicillium fellutanum can enhance nerve growth factor (NGF) synthesis and secretion in vitro.
T32261	Janthitrem F	Janthitrem E monoacetate
	Janthitrem f, as a 10-0-acetyljanthitrem e or janthitrem e monoacetate, is a type ofnaphthopyran. Janthitrem F is prepared by Penicillium janthinellum. Tremorgenic mycotoxi.
T25170	Botryodiplodin	Cytostipin,Antibiotic PSX 1
	Botryodiplodin, an antibiotic, has antileukemic activity from Botryodiplodia theobromae. It has the property of turning the skin of the individual in various shades of pink 2-3 hrs after application. It is a toxic metabo...
T38255	Penipurdin A
	Penipurdin A is an anthraquinone fungal metabolite originally isolated fromP. purpurogenumthat has antibacterial activity.1,2It is active againstM. tuberculosiswith a MIC value of 25 μg/ml.2 1.Xue, J., Fu, Y., Wu, P., et...
T37254	Rugulotrosin A
	Rugulotrosin A is an antibiotic originally isolated from Penicillium. It is active against the Gram-positive bacteria E. faecalis, B. cereus, B. subtilis, and S. aureus with 99% lethal dose (LD99) values of 1.6, 3.1, 5.5...
T35909	Penicinoline
	Penicinoline is an alkaloid that has been found in Penicillium and has antimalarial, insecticidal, and anticancer activities.1,2 It is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50 = ...
T38276	Benzomalvin C
	Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/ml in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50...
T35776	Janthitrem A
	Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. ...
T37288	Remisporine B
	Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp...

Compounds

2-Ethyl-5-methylphenol

Target: Endogenous Metabolite

Olorofim

T27300

Synonym: Olorofim,F901318,F-901318

Target:

Puberuline

T34190

Synonym: Fructigenine A,Rugulosuvine-B,Fructigenine-A,Rugulosuvine B,Puberulin

Synonym: Flavomycelin

N(alpha)-Acetylfusarinines

T33551

Synonym: Nalpha-Acetylfusarinines

Synonym: NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3

Synonym: Janthitrem E monoacetate

Target:

Botryodiplodin

T25170

Synonym: Cytostipin,Antibiotic PSX 1

カタログ番号	製品名	別名	ターゲット
T8693	Diallyl Trisulfide		Apoptosis , Reactive Oxygen Species , Antifungal
	Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.		Apoptosis , Reactive Oxygen Species , Antifungal
T3936	PATULIN	Expansin,Claviform,Clavacin	Apoptosis , Others , Antibacterial , Antibiotic , Autophagy
	Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.		Apoptosis , Others , Antibacterial , Antibiotic , Autophagy
T8335	Lycobetaine acetate	Oxylycorine	Others
	Lycobetaine acetate (Oxylycorine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Ungeremine have strong antibacterial activity against Flavobacterium columnare		Others
T13815	Penicillic acid		Apoptosis , Caspase , Antibacterial , Antibiotic
	Penicillic acid, a polyketide mycotoxin, synthesized by various species of Aspergillus and Penicillium, acts as an inhibitor of Fas ligand-induced apoptosis by impeding self-processing of caspase-8. Additionally, in vitr...		Apoptosis , Caspase , Antibacterial , Antibiotic
T13305	Viridicatol		Anti-infection , Antifungal
	Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg/mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum.		Anti-infection , Antifungal
T70955	Vinaxanthone	SM-345431	Phospholipase , Antibacterial
	Vinaxanthone (SM-345431) is a small molecule compound derived from Penicillium chrysogenum that is a selective and potent semaphorin3A, phospholipase C (PLC), and FabI inhibitor, inhibiting semaphorin3A and FabI.Vinaxant...		Phospholipase , Antibacterial
TN3861	Dihydropinosylvin		Anti-infection
	Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial ...		Anti-infection
T2S1792	Lycobetaine	Ungeremine	Antibacterial
	1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively...		Antibacterial
T31134	Cyclochlorotine	CCRIS 1316
	Cyclochlorotine is a mycotoxin produced by Penicillium insularum, which can cause liver injury and has carcinogenic properties.
T82448	Eremofortin B
	Eremofortin B, a sesquiterpenoid synthesized by Penicillium roqueforti, is also known as PR Toxin (PRT) [1].
T12373	Paxilline		Others
	Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity.		Others
T13629	Cyclo(Ala-Gly)		Others
	Cyclo (Ala-Gly) is a mangrove endophytic fungus, a metabolite of Penicillium thomi, which is cytotoxic to A549, HepG2 and HT29 cells. The IC50 value is in the range of 9.5-18.1 μM.		Others
T73914	Eremofortin A
	Eremofortin A, a metabolite, can be isolated from Penicillium roqueforti cultures [1].
T13872	Roquefortine C		Others
	Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins		Others
T75459	Canadensolide
	Canadensolide is an antifungal metabolite of Penicillium canadense .
T38033	Benzomalvin B
	Benzomalvin B is a fungal metabolite originally isolated from Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μ...
T13608	Chaetoglobosin A		Others
	Chaetoglobosin A, the active compound extracted of Penicillium aquamarinium, is a member of the cytochalasan family. It preferentially induces apoptosis.		Others
T73887	Cycloaspeptide A
	Cycloaspeptide A, obtained from the endophytic fungus Penicillium janczewskii, exhibits antiparasitic properties [1].
T25211	CC 1014	CC1014,CC-1014,NSC-356885,NSC356885,NSC 356885
	CC 1014 is a polypeptide antibiotic isolated from Penicillium lilacinum that inhibits phosphorylation of ADP, Mg ATPase.
T81676	NG-012
	NG-012, a nerve growth factor (NGF) potentiator, was isolated from the culture broth of Penicillium verruculosum F-4542. It enhances neurite outgrowth as induced by NGF in the rat pheochromocytoma cell line (PC12) [1].
T83475	1,3,5,6-Tetrahydroxy-8-methylxanthone
	Compound 8, designated as 1,3,5,6-Tetrahydroxy-8-methylxanthone, is a dimeric 1,4-benzoquinone derivative extracted from the marine-derived Penicillium genus [1].
T82210	Herqueilenone A
	Herqueilenone A, a benzoquinone-chromanon, is derived from the fungus Penicillium herquei FT729 isolated from volcanic soil in Hawaii[1].
TN3373	Albrassitriol		Others
	Albrassitriol is a natural product from the cultures of the fungus Penicillium sp.		Others
T13297	Verruculogen		Others
	Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. Verruculogen inhibits Ca2+-activated K+ channels, and is an M phase inhibitor of the mammalian cell cycle.		Others
T38338	Quinolactacin A
	Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety o...
T82955	Asperazine	(+)-Asperazine
	Asperazine (Compound 5), an alkaloid from Penicillium oxalicum, exhibits moderate activity against HepG2 and CaSki cell lines, with IC50 values exceeding 50 μM [1].
T13618	Citreoviridin		Others
	Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas, in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-depen...		Others
T71750	Quinolactacin A1
	Quinolactacin A1, a powerful acetylcholinesterase (AChE) inhibitor, originates from the solid-state fermentation of Penicillium citrinum 90648. It is utilized in Alzheimer's disease research.
T36931	Penicillide
	Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 μM) and acyl-coenzyme A:cholesterol acyltransferase (A...
T16035	Meleagrin		Others
	Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast mali...		Others
T28379	PF-1163B	PF1163B,(-)-PF1163B,PF 1163B
	PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candid...
T36878	Sclerotiorin
	Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 μM. Sclerotiorin also exhibits a number of other activities including inhibition...
T75444	Peniterphenyl A
	Peniterphenyl A, a deep-sea-derived Penicillium sp. natural product, exhibits inhibitory effects on HSV-1/2 virus entry into cells, potentially by directly interacting with the envelope glycoprotein D, disrupting virus a...
T37690	Phenylpyropene A
	Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM)....
T36438	Sporogen-AO 1
	Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ...
T38108	Fulvic Acid		Antioxidant , PDE
	Fulvic Acid is a natural product of humus produced by microorganisms in soil, sediment or aquatic environments. Fulvic acid is a phenolic acid and fungal metabolite isolated from Penicillium for the first time. Fulvic Ac...		Antioxidant , PDE
T35761	Carviolin
	Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes...