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Search Results for " Toxoplasma "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T1172	Diclazuril	R-64433	Antibiotic , Parasite
	Diclazuril (R-64433) is a coccidiostat.		Antibiotic , Parasite
T25549	JCP174	JCP 174,JCP-174	Serine Protease
	JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.		Serine Protease
T72081	CpCDPK1/TgCDPK1-IN-2		Parasite
	CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can be used in the study of diseases associated with infection of...		Parasite
T78605	CpCDPK1/TgCDPK1-IN-1		Bcr-Abl , Src
	CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.		Bcr-Abl , Src
T36692	Fanotaprim		DHFR
	Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...		DHFR
T72033	PCDPK1/TgCDPK1-IN-3		Parasite
	CpCDPK1/TgCDPK1-IN-3 is a dual inhibitor of CpCDPK1 and TgCDPK1 with an IC50 of 0.003 µM for CpCDPK1 and 0.0036 µM for TgCDPK1. CpCDPK1/TgCDPK1-IN-3 can be used to study infections associated with diseases such as Toxopl...		Parasite
T62333	Anti-Trypanosoma cruzi agent-1
	Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.
T29003	TRC-19
	TRC-19 is a potent and selective inhibitor of Toxoplasma gondii dihydrofolate reductase. TRC-19 shows an IC50 of 9 nM and 89-fold selectivity in favor of Toxoplasma gondii dihydrofolate reductase.
T69311	GW300657X
	GW300657X is a small molecule inhibitor that blocks toxoplasma gondii rhoptry kinase 18 and maintains moderate CDK2-cyclin A inhibitory activity.
T76121	Phosphoglucomutase		Endogenous Metabolite
	Phosphoglucomutase promotes cyst development in Toxoplasma gondii. Deficiency of Phosphoglucomutase causes metabolic disorders.		Endogenous Metabolite
T61671	MMV687807
	MMV687807 is a potent anthelmintic compound exhibiting strong efficacy against Toxoplasma gondii (T. gondii). It demonstrates an IC50 value of 0.15 μM and a CC50 value of 1.69 μM [1].
T38269	Purfalcamine
	Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala...

Compounds

Diclazuril

T1172

Synonym: R-64433

Target: Antibiotic, Parasite

JCP174

T25549

Synonym: JCP 174,JCP-174

Target: Serine Protease

Anti-Trypanosoma cruzi agent-1

Target: Endogenous Metabolite

カタログ番号	製品名	別名	ターゲット
TN7103	13,21-Dihydroeurycomanone	Pasakbumin C	Anti-infection , Parasite
	13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii.		Anti-infection , Parasite
T0819	Spiramycin	Espiramicin,Sequamycin,Rovamycin,Provamycin,Formacidine	Antibacterial , Antibiotic , Parasite
	Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caus...		Antibacterial , Antibiotic , Parasite
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re...

天然物製品

13,21-Dihydroeurycomanone

TN7103

Synonym: Pasakbumin C

Target: Anti-infection, Parasite

Spiramycin

T0819

Synonym: Espiramicin,Sequamycin,Rovamycin,Provamycin,Formacidine

Target: Antibacterial, Antibiotic, Parasite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03635	GRA6 Protein, Toxoplasma gondii, Recombinant (GST)	TOV-Toxoplasma gondii	E. coli
	Major granular component involved in excreted-secreted antigen (ESA) immunity. May have a structural role in the membranous network of the parasitophorous vacuole (PV). GRA6 Protein, Toxoplasma gondii, Recombinant (GST) ...
TMPH-03638	Profilin Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	P. pastoris (Yeast)
	N/A. Profilin Protein, Toxoplasma gondii, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.4 kDa and the accession number is Q58NA1.
TMPH-03631	CDPK1 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	N/A. CDPK1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.3 kDa and the accession number is Q9BJF5.
TMPH-03632	GRA1 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	N/A. GRA1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is P13403.
TMPH-03636	HSP70 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	N/A. HSP70 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 78.9 kDa and the accession number is A0A125YXI9.
TMPH-03634	GRA3 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA...
TMPH-03633	GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc)	Toxoplasma gondii	E. coli
	Major granular component involved in excreted-secreted antigen (ESA) immunity. Possibly acts in conjunction with GRA1. GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) is expressed in E. coli expression system wi...
TMPH-03637	Profilin Protein, Toxoplasma gondii, Recombinant (E. coli, His)	Toxoplasma gondii	E. coli
	N/A. Profilin Protein, Toxoplasma gondii, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.4 kDa and the accession number is Q58NA1.