anti-biofilm | TargetMol

カタログ番号	製品名	別名	ターゲット
T79468	Antimicrobial agent-22
	Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties...
T63500	Alexidine
	Alexidine is an antifungal and anti-biofilm agent against a variety of fungal pathogens. alexidine targets the mitochondrial tyrosine phosphatase PTPMT1 in mammalian cells, causing mitochondrial apoptosis and exhibiting ...
T79561	Mtb-IN-5
	Mtb-IN-5 (compound (-)17j) is an isoxazole exhibiting anti-Mycobacterium tuberculosis (Mtb) activity. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isonia...
T80390	HG4
	HG4 is an antimicrobial peptide with rapid anti-biofilm and anti-inflammatory properties. It exhibits potent activity against Gram-positive pathogens, notably MRSA strains, with a minimum inhibitory concentration (MIC) r...
T80387	HG2
	HG2 is an antimicrobial peptide with rapid action, exhibiting anti-biofilm and anti-inflammatory properties. It is particularly efficacious against Gram-positive pathogens, including MRSA strains (MIC: 16-32 μg/mL), and ...
T79559	Mtb-IN-4
	Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity, with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augmen...
T80526	L-K6L9
	L-K6L9 exhibits antimicrobial and antibiofilm properties effective against P. aeruginosa associated with cystic fibrosis, demonstrating both stability and resistance to degradation by sputum proteases from cystic fibrosi...

Compounds

Antimicrobial agent-22

T79468

カタログ番号	製品名	別名	ターゲット
T36735	3,5-Di-tert-butylphenol		Reactive Oxygen Species , Antifungal
	3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.		Reactive Oxygen Species , Antifungal
T3S1319	(+)-Magnoflorine	Escholin,Magnoflorine,Thalictrin,Escholine	Others , Antifungal
	(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...		Others , Antifungal
T3S1320	(+)-Magnoflorine iodide	Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide	Others , Antifungal
	(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
T4S1321	(+)-Magnoflorine chloride	Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride	Others , Antifungal
	(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
TN1925	Methyl anthranilate		Others , Antibacterial
	Methyl anthranilate is a natural product. Methyl anthranilate is a novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria		Others , Antibacterial
T4723	D-Tagatose	D-(-)-Tagatose,d-tagatos	Others , Endogenous Metabolite
	D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods such as sterilized and...		Others , Endogenous Metabolite
TN1919	(+)-Medioresinol	Medioresinol	Beta Amyloid , ROS , Antifection
	Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α²-secretase, it is a potentially valuable anti...		Beta Amyloid , ROS , Antifection
TN5466	Boeravinone B
	Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for fur...