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T15507 |
Hycanthone
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Etrenol(mesylate),Win 249-33 |
DNA/RNA Synthesis
,
Topoisomerase
,
Parasite
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Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit... |
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T4569 |
Lucanthone
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Lucantona,Lucanthonum |
DNA/RNA Synthesis
,
Autophagy
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Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1). |
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T66154 |
Paroxypropione
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It is an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) |
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T21320 |
Methoxyamine HCl
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TRC102,TRC 102,Methoxyamine,TRC-102 |
Others
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Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is... |
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T35575 |
Aldehyde Reactive Probe (trifluoroacetate salt)
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DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated... |
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T73299 |
APE1-IN-2
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Apoptosis
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APE1-IN-2 (compound AP1), a Pt(IV) proagent, selectively targets the essential base excision repair protein apurinic/apyrimidinic endonuclease 1 (APE1). Exhibiting anticancer properties, APE1-IN-2 prompts the intracellul... |
