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T13920L |
Terlipressin Acetate
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Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous |
Vasopressin Receptor
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Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in... |
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T6991 |
Nitroprusside disodium dihydrate
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Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate |
Guanylate cyclase
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Autophagy
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Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood. |
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T11918 |
Lysipressin
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Lysine vasopressin,[Lys8]-Vasopressin |
Others
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Lysipressin ([Lys8]-Vasopressin), Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. |
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T7601L |
Carbetocin acetate
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Carbetocin acetate(37025-55-1 free base) |
Oxytocin Receptor
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Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. |
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T1514 |
Norethindrone
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Norethisterone |
Estrogen/progestogen Receptor
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Progesterone Receptor
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Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties... |
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T11824LL |
Lanraplenib
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GS-9876 |
Syk
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Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI ... |
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T3536 |
AZD1283
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P2Y Receptor
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AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithromboti... |
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T70349 |
DJT06001
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DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding. |
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T20855 |
Gemeprost
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SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin |
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Gemeprost, an analog of prostaglandin E1, is used for the treatment of obstetric bleeding. It is used to terminate pregnancy up to 24 weeks gestation together with mifepristone. |
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T28237 |
Onapristone
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IVV-1001,ZK 98299,IVV 1001,ZK98299,ZK-98299,IVV1001 |
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Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding. |
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T11824 |
Lanraplenib succinate
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GS-9876 succinate |
Syk
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Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active S... |
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T16377 |
Odiparcil
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SB-424323 |
Thrombin
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Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antit... |
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T36178 |
Aspalatone
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Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Additionally at a minimal effective dose of 24 mg/kg, aspalatone generat... |
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T11824L |
Lanraplenib monosuccinate
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GS-9876 monosuccinate |
Syk
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Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally... |
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T28491 |
R-1663
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R1663 |
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R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner withou... |
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T68681 |
Casuarinin
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Casuarinin is an ellagitannin. It is found in the pericarp of pomegranates. It is also found in Casuarina and Stachyurus species and in Alnus sieboldiana. It is an isomer of casuarictin. It is a highly active carbonic a... |
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T71980 |
Omeprazole acid
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Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are... |
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T64257 |
FXIa-IN-8
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FXIa-IN-8 is a potent and selective inhibitor of FXIa (IC50: 14.2 nM). FXIa-IN-8 exhibits anti-thrombotic effects and does not increase the risk of bleeding or significant toxicity sup>[1]. |
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T0171 |
Norethynodrel
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Lynestrol |
Estrogen/progestogen Receptor
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Norethynodrel (Lynestrol) is a synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contracepti... |
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T7601 |
Carbetocin
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Oxytocin Receptor
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Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. |
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T28099 |
MRS2179
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MRS 2179,MRS-2179 |
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MRS2179 is a competitive P2Y1 receptor antagonist (Kb = 100 nM) with no appreciable activity at P2Y2, P2Y4, or P2Y6 at concentrations up to 30 µM, or at P2Y12 and P2Y13. It inhibits ADP-induced platelet shape change and ... |
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T74647 |
BT5528
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BT5528, a bicyclic peptide toxin conjugate and an EphA2 activator derived from BCY6099, consists of a bicyclic peptide and Auristatin E. This compound demonstrates significant anti-tumor efficacy without inducing bleedin... |
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T79847 |
Frunexian
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EP-7041 |
Factor Xa
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Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa. It demonstrates antithrombotic activity without associated bleeding risk in a rat mesenter... |
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T36553 |
Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
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Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating... |
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T72113 |
6-Aminocaproic acid hydrochloride
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EACA hydrochloride,EACA hydrochloride ; Epsilon-Amino-n-caproic Acid hydrochloride ; 6-Aminohexanoic acid hydrochloride,6-Aminohexanoic acid hydrochloride,Epsilon-Amino-n-caproic Acid hydrochloride |
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6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid derivative, serves as a potent, orally active antifibrinolytic agent by inhibiting plasmin and plasminogen. It functions through competitive binding to lysin... |
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T38178 |
Ristocetin A (sulfate)
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Ristomycin III |
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Ristocetin A, a glycopeptide related to vancomycin, is an antibiotic produced by the microorganism Nocardia lurida[1].
Ristocetin A is currently in clinical use to treat bacterial infections [1]. Ristocetin A is an antib... |
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T36660 |
Olsalazine-13C6
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Olsalazine-13C6 |
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Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that... |
