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T20700 |
Racemetirosine
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Others
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Racemetirosine is an inhibitor of Tyrosine 3-monooxygenase, and consequently it inhibits the synthesis of catecholamines. |
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T22368 |
Metyrosine
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α-Methyltyrosine |
COX
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Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressu... |
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T2568 |
Felypressin
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Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2 |
Vasopressin Receptor
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Felypressin (Octapressin) is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity. |
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T2568L |
Felypressin acetate
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2-(L-Phenylalanine)-8-L-lysinevasopressin,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2 |
Vasopressin Receptor
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Felypressin acetate (PLV-2) is an agonist of vasopressin 1 and acts on all arginine vasopressin receptors 1AS. Felypressin acetate can be used in dental procedures. |
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T19345 |
GP2-114
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Others
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GP2-114 is a catecholamine exercise mimetic that can be used to study coronary artery disease (CAD). |
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TP2058L |
Catestatin acetate
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Catestatin acetate(142211-96-9 free base) |
Endogenous Metabolite
,
AChR
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Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure. |
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T26363L |
Napitane
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A75200,A-75200,A 75200,ABT 200 |
Adrenergic Receptor
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napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the study of depression. |
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T6464 |
Detomidine hydrochloride
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MPV-253 AII,Domosedan,Detomidine HCl |
Adrenergic Receptor
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Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. |
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TP1618L |
PACAP-38 (31-38), human, mouse, rat acetate
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PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base) |
PACAP
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PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY an... |
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T37424 |
CAY10781
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CAY10781 |
Others
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CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosp... |
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TP2158 |
TRV-120027 TFA
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TRV-120027 TFA (1234510-46-3 free base) |
RAAS
,
Arrestin
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TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling. |
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T31570 |
DPBX-L-Dopa
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DPBX L-Dopa |
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DPBX-L-Dopa is a boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors. |
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T80503 |
Proadrenomedullin (N-20) (bovine, porcine)
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ProADM N20(bovine, porcine),PAMP-20(bovine, porcine) |
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Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a peptide known for its strong hypotensive effects and inhibition of catecholamine release from chromaffin cells without competing with other substances. It effe... |
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T24659 |
Prenylamine lactate
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Agozol,Angormin |
|
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Prenylamine lactate is a drug formerly used in the treatment of angina pectoris. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. |
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T30119 |
Arbutamine hydrochloride
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Arbutamine hydrochloride is a catecholamine which acts as a cardiac stimulant. |
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T30630 |
Butopamine
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Butopamine differs from dobutamine in location of only one hydroxyl group, but is no longer a catecholamine. |
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T38610 |
Pirepemat
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IRL752 |
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Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease. |
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TP1618 |
PACAP-38 (31-38), human, mouse, rat
|
|
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PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. |
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T60950 |
Pirepemat fumarate
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|
|
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Pirepemat (IRL752) fumarate can be used in Parkinson's disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2]. |
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T26419 |
A 53693
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A-53693,A53693 |
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A 53693 is a rigid catecholamine and a selective adrenergic agonist. A 53693 has affinity to certain alpha receptor subtypes in rat alpha-2 receptors. |
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T20396 |
Levadopa Related Compound A
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6-Hydroxydopa, L-,L-Hydroxydopa |
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Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent... |
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TP2058 |
Catestatin
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|
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Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signa... |
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TP1619 |
PACAP-38 (16-38), human, mouse, rat
|
|
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PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. |
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T10200 |
9-Hydroxyellipticine hydrochloride
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Others
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TP1490 |
Proadrenomedullin (1-20), human
|
|
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Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from s... |
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T80080 |
PAMP-12 (unmodified) (TFA)
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|
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PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells [1... |
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T60344 |
L-Cytidine
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|
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L-Cytidine is an L-configurational form of Cytidine. L-Cytidine is a pyrimidine nucleoside which is a component of RNA. Cytidine can control the glial glutamate cycle, and affect brain phospholipid metabolism, catecholam... |
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T78027 |
PAMP-12 (unmodified)
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|
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PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from sympathetic nerve endings and adrenal chromaffin cells [1]. |
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T80069 |
PACAP (6-27) (human, ovine, rat)
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Pituitary adenylate cyclase-activating peptide (6-27) |
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PACAP (6-27) (human, ovine, rat) serves as an antagonist for the PACAP receptor, inhibiting the catecholamine response of the canine adrenal gland to vasoactive intestinal peptide (VIP). This compound holds promise for r... |
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T75878 |
Catestatin TFA
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|
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Catestatin TFA, a 21-amino acid residue peptide, exhibits both cationic and hydrophobic properties. This endogenous peptide plays a crucial role in regulating cardiac function and blood pressure. It functions as a non-co... |
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T60677 |
Dobutamine
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|
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Dobutamine is a synthetic catecholamine that can increase cardiac output and correct hypoperfusion. Dobutamine acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors) that is a selective agonist of β1-AR , relatively... |
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T36384 |
DL-Tyrosine-13C9,15N
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L-Tyrosine-13C9,15N |
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L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylal... |
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T83697 |
PAMP-12 (human, mouse, rat, porcine, bovine) TFA
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Proadrenomedullin N-terminal 12 Peptide,PAMP (9-20) |
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Proadrenomedullin N-terminal 12 peptide (PAMP-12), an endogenous fragment originating from the adrenal medulla and spanning amino acids 9-20 of human PAMP-20, plays a role in causing hypotension. It functions as an agoni... |
