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Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T1644 Dopamine hydrochloride 62-31-7 98%
Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
T1457 Deferasirox 201530-41-8 98%
Deferasirox is an oral iron chelating agent used to treat chronic iron overload.
T1482 Ciclopirox 29342-05-0 98%
Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors fo...
T0078L Lapatinib ditosylate 388082-78-8 98%
Lapatinib is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib therapy is associated with tran...
T0907 Sulfasalazine 599-79-1 98%
Sulfasalazine is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug
T6871 L-Glutamic acid monosodium salt 142-47-2 98%
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
T1637 Deferoxamine Mesylate 138-14-7 98%
Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
T6821 Dp44mT 152095-12-0 98%
Dp44mT, a effective iron chelator, has selective antitumor activity.
T0477 Zileuton 111406-87-2 98%
Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the fo...
T2401 Alogliptin Benzoate 850649-62-6 98%
Alogliptin Benzoate(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may...
T1710 Trolox 53188-07-1 98%
Troloxa is a vitamin E analogue, used in reducing oxidative stress or damage.
T2887 Trigonelline 535-83-1 98%
Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
T1885 Siramesine hydrochloride 224177-60-0 98%
Siramesine (Lu 28-179) hydrochloride is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent antic...
T1622 Rosiglitazone maleate 155141-29-0 98%
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity...
T2858 Baicalein 491-67-8 98%
Baicalein is a xanthine oxidase inhibitor.
T0423 Ethylenediaminetetraacetic acid trisodium salt 150-38-9 98%
Edetate Trisodiumis used to bind metal ions in the chelation therapy.
T8662 UAMC-3203 hydrochloride 2271358-65-5 98%
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
T1207 Lovastatin 75330-75-5 98%
Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
T3116 Atorvastatin hemicalcium salt 134523-03-8 98%
Atorvastatin hemicalcium salt, an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
T7708 DL-Buthionine-(S,R)-sulfoximine 5072-26-4 98%
D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
Dopamine hydrochloride
T1644
Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine b...
Deferasirox
T1457
Deferasirox is an oral iron chelating agent used to treat chronic iron overload.
Ciclopirox
T1482
Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors fo...
Lapatinib ditosylate
T0078L
Lapatinib is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib therapy is associated with tran...
Sulfasalazine
T0907
Sulfasalazine is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug
L-Glutamic acid monosodium salt
T6871
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
Deferoxamine Mesylate
T1637
Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
Dp44mT
T6821
Dp44mT, a effective iron chelator, has selective antitumor activity.
Zileuton
T0477
Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the fo...
Alogliptin Benzoate
T2401
Alogliptin Benzoate(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may...
Trolox
T1710
Troloxa is a vitamin E analogue, used in reducing oxidative stress or damage.
Trigonelline
T2887
Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
Siramesine hydrochloride
T1885
Siramesine (Lu 28-179) hydrochloride is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent antic...
Rosiglitazone maleate
T1622
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity...
Baicalein
T2858
Baicalein is a xanthine oxidase inhibitor.
Ethylenediaminetetraacetic acid trisodium salt
T0423
Edetate Trisodiumis used to bind metal ions in the chelation therapy.
UAMC-3203 hydrochloride
T8662
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
Lovastatin
T1207
Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
Atorvastatin hemicalcium salt
T3116
Atorvastatin hemicalcium salt, an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
DL-Buthionine-(S,R)-sulfoximine
T7708
D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
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