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Search Results for " disulfide bonds "

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17

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1

天然化合物

36

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1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T20470 Edetic acid Ethylenediaminetetraacetic acid,EDTA Others
Edetic acid (Ethylenediaminetetraacetic acid) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
TP2325L Endotoxin Inhibitor acetate Endotoxin Inhibitor acetate(147396-10-9 free base) Others
Endotoxin Inhibitor acetate has a strong blocking effect on bacterial physiological activity, thus producing antibacterial toxin Inhibitor sequences with disulfide bonds and a large amount of lysine. Endotoxin Inhibitor ...
T6741 SPDP SPDP Crosslinker Others
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ...
T3161L BACE-IN-1 acetate BACE-IN-1 acetate (350228-37-4,Free base) BACE
BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4,Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c...
T11057 DM3-SMe Others
DM3-SMe is a maytansine derivative and tubulin inhibitor. It is a cytotoxic part of antibody-drug conjugates (ADCs) and can bind to antibodies via disulfide bonds or stable thioether bonds. DM3-SMe has high cytotoxic act...
T31584 DST Crosslinker DST Cross linker,DST Cross-linker
DST crosslinker(disuccinimide tartarate) is an isotype bifunctional, cleavable crosslinker (cleavable by an oxidizer) for applications that require crosslinking cleavability and that do not interfere with protein disulfi...
T35456 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds f...
T40153 BAMEA-O16B BAMEA-O16B
BAMEAO16B is a lipid nanoparticle that incorporates disulfide bonds for efficient delivery of Cas9 mRNA and sgRNA into cells. In the intracellular environment, BAMEAO16B responds to reduction by releasing RNA, facilitati...
T11059 DM4-SMe Others
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds ...
T82255 GsAF-1
GsAF-1, a peptide toxin with three disulfide bonds, is derived from the venom of the Chilean pink tarantula and has potential applications in the research of moderate-to-severe pain [1].
T17834 DM4-SPDP Others
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin...
T80078 Calciseptin Calcium Channel
Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1...
TP1971 Pseudo RACK1
Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector ...
T77908 Farletuzumab ecteribulin MORAb-202
Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-...
TP2259 Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] Others
Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition m...
TP2260 Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] Others
Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the anti...
T80249 Epsilon-V1-2, Cys-conjugated PKC
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...
カタログ番号 製品名 別名 ターゲット
T1085 L-Glutathione reduced GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00735 PDGF-BB Protein, Human, Recombinant Human E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00562 PDGF-BB Protein, Mouse, Recombinant (His) Mouse E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-00395 Insulin Protein, Human, Recombinant Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPH-02197 TXNDC5 Protein, Human, Recombinant Human E. coli
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression sy...
TMPJ-00461 PDIA5 Protein, Human, Recombinant (His) Human HEK293 Cells
Protein disulfide-isomerase A5 is a 519 amino acids protein that belongs to the protein disulfide isomerase family.It contains 3 thioredoxin domains.It can catalyze the rearrangement of -S-S- bonds in proteins.
TMPH-02196 TXNDC5 Protein, Human, Recombinant (GST) Human E. coli
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli express...
TMPY-02887 IFI30 Protein, Human, Recombinant (His) Human HEK293 Cells
IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat...
TMPJ-01020 GFER Protein, Human, Recombinant (His) Human E. coli
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isofo...
TMPY-02890 ERP27 Protein, Human, Recombinant (mFc) Human HEK293 Cells
ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide...
TMPJ-01124 PDIA6 Protein, Human, Recombinant (His) Human HEK293 Cells
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPH-00789 Hamster polyomavirus (HaPyV) VP1 Protein (His & Myc) HaPyV E. coli
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with sialic acids on...
TMPJ-01274 ERO1L Protein, Human, Recombinant (His) Human HEK293 Cells
ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endopl...
TMPH-00708 DegP Protein, E. coli, Recombinant (His) E. coli P. pastoris (Yeast)
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo...
TMPJ-00301 Coagulation Factor X Protein, Human, Recombinant (hFc) Human HEK293 Cells
F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a...
TMPJ-00500 Kappa-Casein Protein, Human, Recombinant (His) Human HEK293 Cells
Kappa-Casein (CSN3) is a secreted protein that belongs to the Kappa-Casein family. CSN3 exists in heteromultimers that are composed of alpha-s 1casein and kappa casein linked by disulfide bonds. CSN3 is involved in a nu...
TMPJ-01243 DEFB4 Protein, Human, Recombinant Human E. coli
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1,...
TMPJ-00759 VDB Protein, Human, Recombinant (His) Human HEK293 Cells
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. D...
TMPJ-01015 INHBC Protein, Human, Recombinant (C-His) Human HEK293 Cells
Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disul...
TMPJ-01079 TFF2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, T...
TMPJ-00003 DEFB1 Protein, Human, Recombinant Human E. coli
β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a si...
TMPJ-00906 CRHBP Protein, Human, Recombinant (His) Human HEK293 Cells
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and de...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His) Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPJ-00597 IgG1 hFc Protein, Mouse, Recombinant Mouse HEK293 Cells
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-01173 TFF3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle...
TMPJ-00707 Coagulation factor X/F10 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin ...
TMPJ-00058 BTC Protein, Mouse, Recombinant (His) Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Be...
TMPJ-00667 DEFB4A Protein, Human, Recombinant Human E. coli
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of t...
TMPJ-00082 NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPJ-01440 Cutinase Protein, Thermobifida fusca, Recombinant (His) Thermobifida fusca E. coli
Cutinase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is cutin hydrolase. Cutinase is a serine esterase containing the classical Ser, ...
TMPJ-00100 Artemin Protein, Human, Recombinant Human E. coli
Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a variable length pre-, or signal sequence, plus a 68 amino acid (...
TMPY-02845 CST9L Protein, Human, Recombinant (hFc) Human HEK293 Cells
Testatin is a member of the Cystatin family. Cystatins comprise genes that all show expression patterns that are strikingly restricted to reproductive tissue. Cystatins are a family of cysteine protease inhibitors with h...
TMPJ-00398 IL-12RB2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits tha...
TMPY-02077 Cystatin A Protein, Human, Recombinant (His) Human E. coli
Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is locate...
TMPY-02090 Cystatin B Protein, Human, Recombinant (His) Human E. coli
Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinas...
TMPJ-00751 IgG4 hFc Protein, Human, Recombinant (aa 99-326) Human HEK293 Cells
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
PDGF-BB Protein, Human, Recombinant
TMPJ-00735
Species: Human
Expression System: E. coli
PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Species: Mouse
Expression System: E. coli
Insulin Protein, Human, Recombinant
TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
TMPY-01104
Species: Human
Expression System: HEK293 Cells
TXNDC5 Protein, Human, Recombinant
TMPH-02197
Species: Human
Expression System: E. coli
PDIA5 Protein, Human, Recombinant (His)
TMPJ-00461
Species: Human
Expression System: HEK293 Cells
TXNDC5 Protein, Human, Recombinant (GST)
TMPH-02196
Species: Human
Expression System: E. coli
IFI30 Protein, Human, Recombinant (His)
TMPY-02887
Species: Human
Expression System: HEK293 Cells
GFER Protein, Human, Recombinant (His)
TMPJ-01020
Species: Human
Expression System: E. coli
ERP27 Protein, Human, Recombinant (mFc)
TMPY-02890
Species: Human
Expression System: HEK293 Cells
PDIA6 Protein, Human, Recombinant (His)
TMPJ-01124
Species: Human
Expression System: HEK293 Cells
Hamster polyomavirus (HaPyV) VP1 Protein (His & Myc)
TMPH-00789
Species: HaPyV
Expression System: E. coli
ERO1L Protein, Human, Recombinant (His)
TMPJ-01274
Species: Human
Expression System: HEK293 Cells
DegP Protein, E. coli, Recombinant (His)
TMPH-00708
Species: E. coli
Expression System: P. pastoris (Yeast)
Coagulation Factor X Protein, Human, Recombinant (hFc)
TMPJ-00301
Species: Human
Expression System: HEK293 Cells
Kappa-Casein Protein, Human, Recombinant (His)
TMPJ-00500
Species: Human
Expression System: HEK293 Cells
DEFB4 Protein, Human, Recombinant
TMPJ-01243
Species: Human
Expression System: E. coli
VDB Protein, Human, Recombinant (His)
TMPJ-00759
Species: Human
Expression System: HEK293 Cells
INHBC Protein, Human, Recombinant (C-His)
TMPJ-01015
Species: Human
Expression System: HEK293 Cells
TFF2 Protein, Mouse, Recombinant (His)
TMPJ-01079
Species: Mouse
Expression System: HEK293 Cells
DEFB1 Protein, Human, Recombinant
TMPJ-00003
Species: Human
Expression System: E. coli
CRHBP Protein, Human, Recombinant (His)
TMPJ-00906
Species: Human
Expression System: HEK293 Cells
NRROS Protein, Mouse, Recombinant (His)
TMPH-02803
Species: Mouse
Expression System: E. coli
IgG1 hFc Protein, Mouse, Recombinant
TMPJ-00597
Species: Mouse
Expression System: HEK293 Cells
TFF3 Protein, Mouse, Recombinant (His)
TMPJ-01173
Species: Mouse
Expression System: HEK293 Cells
Coagulation factor X/F10 Protein, Mouse, Recombinant (His)
TMPJ-00707
Species: Mouse
Expression System: HEK293 Cells
BTC Protein, Mouse, Recombinant (His)
TMPJ-00058
Species: Mouse
Expression System: E. coli
DEFB4A Protein, Human, Recombinant
TMPJ-00667
Species: Human
Expression System: E. coli
NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)
TMPJ-00082
Species: Mouse
Expression System: HEK293 Cells
Cutinase Protein, Thermobifida fusca, Recombinant (His)
TMPJ-01440
Species: Thermobifida fusca
Expression System: E. coli
Artemin Protein, Human, Recombinant
TMPJ-00100
Species: Human
Expression System: E. coli
CST9L Protein, Human, Recombinant (hFc)
TMPY-02845
Species: Human
Expression System: HEK293 Cells
IL-12RB2 Protein, Mouse, Recombinant (hFc)
TMPJ-00398
Species: Mouse
Expression System: HEK293 Cells
Cystatin A Protein, Human, Recombinant (His)
TMPY-02077
Species: Human
Expression System: E. coli
Cystatin B Protein, Human, Recombinant (His)
TMPY-02090
Species: Human
Expression System: E. coli
IgG4 hFc Protein, Human, Recombinant (aa 99-326)
TMPJ-00751
Species: Human
Expression System: HEK293 Cells