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T12192 |
NCGC00229600
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Others
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TSH Receptor
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NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. |
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T38612 |
Linaprazan glurate
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Others
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Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. |
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T19023 |
Lucigenin
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NSC-151912,L-6868 |
Others
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Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells. |
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T19039 |
NIR-Thiol dinitrobenzenesulfonate
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Others
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NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. It is capable of imaging endogenously produced thiol in living cells and mice. |
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T36833 |
A6770
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A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P l... |
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T71212 |
Lornoxicam-d4
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Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and an... |
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T28140 |
NCG21
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NCG-21,NCG 21 |
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NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine... |
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T37409 |
DPC-AJ1951 (trifluoroacetate salt)
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DPC-AJ1951 (trifluoroacetate salt) |
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DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogen... |
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T37634 |
17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
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Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by asp... |
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T37633 |
17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
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17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2... |
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T37199 |
Bilaid C
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Bilaid C is a tetrapeptide μ-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293... |
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T82771 |
CB2-H
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CB2-H is a dual-channel fluorescent probe designed for the concurrent detection of HOCl and ONOO- with two separate channels that avoid spectral cross-interference. It facilitates dual-channel fluorescence imaging to mon... |
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T37503 |
Maresin 2
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3R,14S-diHDHA |
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Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.[1] [2] Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human mac... |
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T31916 |
Gaxilose
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4-Galactosylxylose,4-O-Galactosyl-D-xylose,4-O-Galactosylxylose |
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Gaxilose, also known as 4-Galactosylxylose, a synthetic disaccharide and a substrate of intestinal lactase. Gaxilose is used in a new noninvasive diagnostic test based on urine or serum measurement of D-xylose after lact... |
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T74693 |
CDN-A
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CDN-A, a cyclic di-nucleotide, serves as a precursor for synthesizing antibody-drug conjugates (ADC) and acts as a potent stimulator of both innate and adaptive immune responses. In humans, these cyclic di-nucleotides, p... |
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T37606 |
Resolvin D5
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7(S),17(S)-diHDHA |
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Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory respons... |
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T35696 |
Olomoucine II
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Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs; IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 μM for Cdk1, -2, -4, -7, and -9, respectively).1It is selective for CDKs over 10 additional kinases (IC50s = >100 μM... |
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T83764 |
Sulfane Sulfur Probe 4
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SSP4 |
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Sulfane Sulfur Probe 4 (SSP4) serves as a fluorescent probe targeting sulfane sulfur species, encompassing hydrogen sulfide-derived polysulfides, hydropersulfides, and persulfides generated endogenously. Upon interacting... |
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T35946 |
17(R)-Resolvin D1
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Aspirin-triggered Resolvin D1,17(R)-Resolvin D1 |
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Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response ... |
