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Search Results for " endosome "

ターゲット

4

阻害剤

22

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T14919 CDKI-73 Apoptosis , CDK
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effe...
T8903 Retro-2 Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino} Others , Virus Protease , Parasite , Autophagy
Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Go...
TP2505L LAH4 acetate KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base) Antibacterial
LAH4 acetate is the α-helical structure of the designed amphoteric peptide antibiotic, which is capable of complexing DNA, associating with the cell surface membrane and wrapped in the endosome, which is destroyed with t...
T80375 Human α-defensin 5 Parasite
Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-1.25 μM specifically for HPV16. It functions by binding to t...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-01192 ELAPOR1 Protein, Human, Recombinant (His) Human HEK293 Cells
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated wi...
TMPH-03691 VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc) VSIV E. coli
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between ...
TMPH-02301 VPS35 Protein, Human, Recombinant (His & Myc) Human E. coli
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transm...
TMPH-02127 SNX16 Protein, Human, Recombinant (His) Human E. coli
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF si...
TMPH-03222 Rabies virus (RABV) (strain ERA) Glycoprotein (His) RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03221 Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO) RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03224 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His) RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03219 Rabies virus (RABV) (strain India) Glycoprotein (His) RABV P. pastoris (Yeast)
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03220 Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO) RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPJ-00053 PRL-2 Protein, Human, Recombinant (His) Human E. coli
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ...
TMPH-03223 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His) RABV Baculovirus Insect Cells
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-02395 Lassa virus (strain GA391) GPC Protein (His) LASV E. coli
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induc...
TMPY-02419 LMAN2 Protein, Human, Recombinant (His) Human E. coli
LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membra...
TMPH-02538 Beclin-1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways...
TMPH-02348 Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc) H1N1 E. coli
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th...
TMPJ-00845 CTSE Protein, Human, Recombinant (His) Human HEK293 Cells
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is loca...
TMPJ-00264 LAMP1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysoso...
TMPH-02347 Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His) H1N1 E. coli
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of th...
TMPH-02539 MGAT3 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannos...
TMPY-01996 SorCS1 Protein, Human, Recombinant (His) Human HEK293 Cells
VPS1 domain-containing receptor SorCS1, also known as SORCS1 and SORCS, is a single-pass type I membrane protein that belongs to the SORCS family and SORCS1 subfamily. SORCS1 contains five BNR repeats and one PKD domain....
TMPH-01692 MAPK3 Protein, Human, Recombinant (His) Human E. coli
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPH-03741 BoNT/F Protein, Clostridium botulinum, Recombinant (His) Clostridium botulinum E. coli
Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequen...
ELAPOR1 Protein, Human, Recombinant (His)
TMPJ-01192
Species: Human
Expression System: HEK293 Cells
VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc)
TMPH-03691
Species: VSIV
Expression System: E. coli
VPS35 Protein, Human, Recombinant (His & Myc)
TMPH-02301
Species: Human
Expression System: E. coli
SNX16 Protein, Human, Recombinant (His)
TMPH-02127
Species: Human
Expression System: E. coli
Rabies virus (RABV) (strain ERA) Glycoprotein (His)
TMPH-03222
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)
TMPH-03221
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)
TMPH-03224
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain India) Glycoprotein (His)
TMPH-03219
Species: RABV
Expression System: P. pastoris (Yeast)
Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)
TMPH-03220
Species: RABV
Expression System: E. coli
PRL-2 Protein, Human, Recombinant (His)
TMPJ-00053
Species: Human
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)
TMPH-03223
Species: RABV
Expression System: Baculovirus Insect Cells
Lassa virus (strain GA391) GPC Protein (His)
TMPH-02395
Species: LASV
Expression System: E. coli
LMAN2 Protein, Human, Recombinant (His)
TMPY-02419
Species: Human
Expression System: E. coli
Beclin-1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02538
Species: Mouse
Expression System: E. coli
Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)
TMPH-02348
Species: H1N1
Expression System: E. coli
CTSE Protein, Human, Recombinant (His)
TMPJ-00845
Species: Human
Expression System: HEK293 Cells
LAMP1 Protein, Human, Recombinant (hFc)
TMPJ-00264
Species: Human
Expression System: HEK293 Cells
Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)
TMPH-02347
Species: H1N1
Expression System: E. coli
MGAT3 Protein, Mouse, Recombinant (His & Myc)
TMPH-02539
Species: Mouse
Expression System: E. coli
SorCS1 Protein, Human, Recombinant (His)
TMPY-01996
Species: Human
Expression System: HEK293 Cells
MAPK3 Protein, Human, Recombinant (His)
TMPH-01692
Species: Human
Expression System: E. coli
BoNT/F Protein, Clostridium botulinum, Recombinant (His)
TMPH-03741
Species: Clostridium botulinum
Expression System: E. coli