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カタログ番号 | 製品名 | 別名 | ターゲット |
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T23383 | SR11237 | SR 11237 | Others , RAR/RXR |
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | |||
T26859 | BMS-8 | PD-1/PD-L1 | |
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers. | |||
T78870 | TWIK-1/TREK-1-IN-3 | Potassium Channel | |
TWIK-1/TREK-1-IN-3 is a selective and potent inhibitor of potassium channel TREK-1, inhibiting TREK-1 homodimers and TWIK-1/TREK-1 heterodimers containing two-pore-domain potassium (K2p) channels.TWIK-1/TREK-1-IN-3 exhib... | |||
T32107 | HX-603 | HX 603 | |
HX-603 is a selectivity agonist of RXR that inhibits the activation of RAR-RXR heterodimers as well as RXR homodimers. | |||
T78868 | TWIK-1/TREK-1-IN-1 | Potassium Channel | |
Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, both significant for its role as a... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-01471 | Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant | Human/Mouse/Rat | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi... | |||
TMPY-03407 | NQO1 Protein, Human, Recombinant (His) | Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-... | |||
TMPY-02888 | MAX Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m... | |||
TMPY-03974 | Bim Protein, Human, Recombinant (His) | Human | E. coli |
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. ... | |||
TMPJ-00931 | Serpin A4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec... | |||
TMPJ-00046 | IL-17F Protein, Human, Recombinant | Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally relate... | |||
TMPY-03434 | BMF Protein, Human, Recombinant (His) | Human | E. coli |
BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF... | |||
TMPJ-00363 | IL-12RB1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL1... | |||
TMPJ-01089 | TFF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing... | |||
TMPJ-00397 | IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to I... | |||
TMPJ-00716 | Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His) | Human | HEK293 Cells |
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to D... | |||
TMPY-02797 | TXNL4A Protein, Human, Recombinant (His) | Human | E. coli |
DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their ro... | |||
TMPJ-00058 | BTC Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Be... | |||
TMPY-00004 | CD28 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ... | |||
TMPJ-00385 | CDH6 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as... | |||
TMPY-01618 | GLO1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyox... | |||
TMPY-02723 | TXNL4B Protein, Human, Recombinant (His) | Human | E. coli |
Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in c... | |||
TMPY-01052 | R-Cadherin/CDH4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) region... |
カタログ番号 | 製品名 | ||
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L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; |