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Search Results for " homodimers "

ターゲット

5

阻害剤

18

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T23383 SR11237 SR 11237 Others , RAR/RXR 
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
T26859 BMS-8 PD-1/PD-L1
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
T78870 TWIK-1/TREK-1-IN-3 Potassium Channel
TWIK-1/TREK-1-IN-3 is a selective and potent inhibitor of potassium channel TREK-1, inhibiting TREK-1 homodimers and TWIK-1/TREK-1 heterodimers containing two-pore-domain potassium (K2p) channels.TWIK-1/TREK-1-IN-3 exhib...
T32107 HX-603 HX 603
HX-603 is a selectivity agonist of RXR that inhibits the activation of RAR-RXR heterodimers as well as RXR homodimers.
T78868 TWIK-1/TREK-1-IN-1 Potassium Channel
Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, both significant for its role as a...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-01471 Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant Human/Mouse/Rat HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi...
TMPY-03407 NQO1 Protein, Human, Recombinant (His) Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-...
TMPY-02888 MAX Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m...
TMPY-03974 Bim Protein, Human, Recombinant (His) Human E. coli
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. ...
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec...
TMPJ-00046 IL-17F Protein, Human, Recombinant Human E. coli
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally relate...
TMPY-03434 BMF Protein, Human, Recombinant (His) Human E. coli
BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF...
TMPJ-00363 IL-12RB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL1...
TMPJ-01089 TFF1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing...
TMPJ-00397 IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to I...
TMPJ-00716 Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His) Human HEK293 Cells
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to D...
TMPY-02797 TXNL4A Protein, Human, Recombinant (His) Human E. coli
DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their ro...
TMPJ-00058 BTC Protein, Mouse, Recombinant (His) Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Be...
TMPY-00004 CD28 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPJ-00385 CDH6 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as...
TMPY-01618 GLO1 Protein, Mouse, Recombinant (His) Mouse E. coli
Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyox...
TMPY-02723 TXNL4B Protein, Human, Recombinant (His) Human E. coli
Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in c...
TMPY-01052 R-Cadherin/CDH4 Protein, Human, Recombinant (His) Human HEK293 Cells
The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) region...
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
TMPJ-01471
Species: Human/Mouse/Rat
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
TMPY-03407
Species: Human
Expression System: E. coli
MAX Protein, Human, Recombinant (His & GST)
TMPY-02888
Species: Human
Expression System: Baculovirus Insect Cells
Bim Protein, Human, Recombinant (His)
TMPY-03974
Species: Human
Expression System: E. coli
Serpin A4 Protein, Human, Recombinant (His)
TMPJ-00931
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant
TMPJ-00046
Species: Human
Expression System: E. coli
BMF Protein, Human, Recombinant (His)
TMPY-03434
Species: Human
Expression System: E. coli
IL-12RB1 Protein, Human, Recombinant (hFc)
TMPJ-00363
Species: Human
Expression System: HEK293 Cells
TFF1 Protein, Mouse, Recombinant (His)
TMPJ-01089
Species: Mouse
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00397
Species: Human
Expression System: HEK293 Cells
Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
TMPJ-00716
Species: Human
Expression System: HEK293 Cells
TXNL4A Protein, Human, Recombinant (His)
TMPY-02797
Species: Human
Expression System: E. coli
BTC Protein, Mouse, Recombinant (His)
TMPJ-00058
Species: Mouse
Expression System: E. coli
CD28 Protein, Rat, Recombinant (hFc)
TMPY-00004
Species: Rat
Expression System: HEK293 Cells
CDH6 Protein, Human, Recombinant (hFc)
TMPJ-00385
Species: Human
Expression System: HEK293 Cells
GLO1 Protein, Mouse, Recombinant (His)
TMPY-01618
Species: Mouse
Expression System: E. coli
TXNL4B Protein, Human, Recombinant (His)
TMPY-02723
Species: Human
Expression System: E. coli
R-Cadherin/CDH4 Protein, Human, Recombinant (His)
TMPY-01052
Species: Human
Expression System: HEK293 Cells
カタログ番号 製品名
L3800 NF-κB Signaling Compound Library

729 compounds
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;