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Search Results for " myasthenia "

ターゲット

15

阻害剤

3

天然化合物

1

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T9989 AChE-IN-27 Others
AChE-IN-27 is a small molecule used for high-throughput assays.
T1612 Neostigmine methyl sulfate Normastigmin,Hodostin,Syntostigmin AChR , AChE
Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.
T8631 Pyridostigmine Regonol,Mestinon-SR,UNII-19QM69HH21,PyridostigmineBromine,Pyridostigminum Others
Pyridostigmine(Regonol) is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate.
T0780 Pyridostigmine bromide Mestinon AChE
Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.
T76867 Ravulizumab ALXN1210 Complement System
Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity to block complement activation. Ravulizumab can be used fo...
T7825 Distigmine Bromide BC 51,Ubretid,BC51,Hexamarium,BC-51
Distigmine Bromide is an acetylcholinesterase inhibitor. It is used for the treatment of underactive neurogenic bladder and myasthenia gravis.
T69158 Ambenonium chloride tetrahydrate
Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav...
T71758 Ambenonium chloride
Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav...
T69029 Neostigmine
Neostigmine is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross th...
T83182 AChRα(97-116)
AChRα(97-116), a peptide implicated in experimental autoimmune myasthenia gravis (EAMG) induction, serves as a targeted agent in this autoimmune disorder [1].
T69472 Edrophonium
Edrophonium is a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
T69050 Neostigmine hydroxide
Neostigmine hydroxide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does no...
T33638 Neostigmine Iodide SB 24,SB24,TL1321,TL 1321,TL-1321,SB-24
Neostigmine Iodide is a parasympathic compound used as a reversible acetylcholinesterase inhibitor to improve muscle tone in patients with myasthenia gravis and in routine anesthesia to reverse the effects of non-depolar...
T4497L Amifampridine phosphate BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760
Amifampridine is mainly used to treat many rare muscle diseases. In the United States, aminopyridine is being studied for the treatment of Lambert-Eaton myasmus syndrome (LEMS). Amifampridine is also used to treat many c...
T74690 Monarsen
Monarsen (EN101), a synthetic 20-base antisense oligodeoxynucleotide targeting the human AChE gene, is utilized in researching autoimmune myasthenia gravis (MG). This neuromuscular disorder is characterized by autoantibo...
カタログ番号 製品名 別名 ターゲット
T2S1200 Sinapine Antioxidant , P-gp , AChE
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities.
T3392 Sinapine thiocyanate P-gp , AChE
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o...
T38606 Sinapine hydroxide
Sinapine hydroxide, an alkaloid derived from the seeds of cruciferous plants, demonstrates a variety of beneficial properties including anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic, and radio-protective e...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02045 SECTM1 Protein, Human, Recombinant (His) Human HEK293
Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern a...