|
T14830 |
Bromperidol
|
R-11333 |
5-HT Receptor
|
|
Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia. |
|
T0972 |
Isoniazid
|
INH,Isonicotinic acid hydrazide,Isonicotinic hydrazide |
Mitophagy
,
Dehydrogenase
,
CAT
,
Antibacterial
,
Autophagy
|
|
Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic. |
|
T60073 |
Antimycobacterial agent-4
|
4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide |
Antibacterial
|
|
Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis. |
|
T63420 |
Antimycobacterial agent-2
|
|
|
|
Antimycobacterial agent-2 is an effective anti-mycobacterial agent with a MIC99 of 0.8 μM against Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 is cytotoxic, acting on CHO cells (IC50: 48.1 μM). |
|
T61853 |
Antimycobacterial agent-1
|
|
|
|
Antimycobacterial agent-1 (compound 33) demonstrates potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimal inhibitory concentration (MIC) value of 1 μg/ml. Notably, antimycobacterial ... |
|
T72306 |
Mycobacterial Zmp1-IN-1
|
|
|
|
Mycobacterial Zmp1-IN-1, a zinc metalloprotease-1 (Zmp1) inhibitor, demonstrates dose-dependent anti-mycobacterial activity against Mtb H37Ra, making it suitable for tuberculosis (TB) research. |
|
T79281 |
Antimycobacterial agent-6
|
|
|
|
Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting the Mtb DprE1-C387S mutant. It displays minimal inhibitory ... |
|
T63865 |
Antimycobacterial agent-3
|
|
|
|
Antimycobacterial agent-3 is an antimycobacterial agent with low cytotoxicity. antimycobacterial agent-3 is effective against sensitive MTB strain H37Rv and resistant clinical isolates (MIC < 0.029-0.110 μ M). |
|
T7518 |
Deoxycytidine triphosphate trisodium salt
|
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI |
Nucleoside Antimetabolite/Analog
,
DNA/RNA Synthesis
,
Endogenous Metabolite
,
Antibiotic
|
|
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria. |
|
T21023 |
Bedaquiline fumarate
|
TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323 |
Antibacterial
,
Antibiotic
|
|
Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ... |
|
T0377 |
Clofazimine
|
NSC-141046 |
DNA
,
Antibacterial
,
Antibiotic
|
|
Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria. |
|
T23979 |
Deoxypheganomycin D
|
|
|
|
Deoxypheganomycin D is a specific mycobacteria inhibitor. |
|
T26189 |
Setomimycin
|
AM 2947,Antibiotic A 39183B,AM2947,AM-2947 |
|
|
Setomimycin is an antibiotic against Gram positive bacteria, including mycobacteria. |
|
T25955 |
Picromycin
|
Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin |
|
|
Picromycin is a 14-membered macrolide antibiotic and Prolyl endopeptidase (PREP) inhibitor. Pikromycin shows activity against gram-positive bacteria including mycobacteria. |
|
T33537 |
Mycobactin P
|
|
|
|
Mycobactin P is one of iron(III) chelating compounds produced by most species of Mycobacteria which act as growth factors. |
|
T40520 |
Thiophene-2
|
Thiophene-2,TP2 |
|
|
Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis. By doing so, it effectively induces rapid cell death in mycobacteria. Thiophene-2 d... |
|
T62840 |
Bromperidol hydrochloride
|
|
|
|
Bromperidol hydrochloride (R-11333 hydrochloride) is an antipsychotic agent with good affinity for the central dopamine receptors D2. Spectinomycin synergistically kills mycobacteria. |
|
T16749 |
Rifalazil
|
KRM-1648,ABI-1648 |
DNA/RNA Synthesis
|
|
|
|
T73271 |
MMV688845
|
(R)-GSK1729177A |
|
|
MMV688845 is a bactericidal nontuberculous mycobacteria (NTM) RNA polymerase inhibitor that exhibits anti-tuberculosis efficacy and is effective against Mycobacterium abscessus. |
|
T60486 |
Mycobactin-IN-1
|
|
|
|
Mycobactin-IN-1 (compound 44) is a pyrazoline analogue. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA) which is a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 is an inhibitor of mycobactin biosy... |
|
T63786 |
WX-081
|
|
|
|
WX-081 is an anti-tuberculosis agent that exhibits significant anti-mycobacterial effects against M. tuberculosisH37Rv and is able to act on drug-susceptible (DS-TB) mycobacteria (MIC: 0.083 μg/ml) and multidrug-resistan... |
|
T75313 |
Methdilazine
|
|
|
|
Methdilazine, an orally active (histamine antagonist) antibiotic, demonstrates the ability to inhibit various mycobacteria with minimum inhibitory concentration (MIC) values ranging from 5-15 μg/mL both in vitro and in v... |
|
T83940 |
SCy5DL-amide
|
|
|
|
sCy5DL-amide is a fluorescent D-amino acid designed for peptidoglycan labeling across a broad spectrum of bacteria, encompassing gram-positive, gram-negative, and mycobacteria strains. It demonstrates exceptional incorpo... |
|
T83939 |
SCy5DA
|
|
|
|
sCy5DA, a fluorescent D-amino acid, is designed for annotating peptidoglycans in live bacteria, facilitating the imaging of a broad spectrum of bacterial types, including gram-positive, gram-negative, and mycobacteria, w... |
