|
T2200 |
Hydroxyzine dihydrochloride
|
Hydroxyzine 2HCl |
Histamine Receptor
|
|
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... |
|
T0082 |
Domperidone
|
R33812 |
Dopamine Receptor
|
|
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z... |
|
T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
|
T4616 |
Metoclopramide
|
5-Chloro-2-methoxyprocainamide |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ... |
|
T8385 |
Metoclopramide hydrochloride hydrate
|
Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic |
|
T11326 |
Frovatriptan succinate hydrate
|
Frovelan,Frova |
5-HT Receptor
|
|
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b... |
|
T1528 |
Azasetron hydrochloride
|
Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl |
5-HT Receptor
|
|
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic. |
|
T0424 |
Bismuth Subsalicylate
|
Bismuth subsalicylat,Bismuth(III) salicylate basic,Bismuth oxysalicylate |
COX
,
PGE Synthase
|
|
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts ... |
|
T1478 |
Ondansetron hydrochloride dihydrate
|
SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride |
5-HT Receptor
|
|
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a... |
|
T1790 |
Fosaprepitant dimeglumine
|
L785298,MK-0517,Fosaprepitant dimeglumine salt |
Neurokinin receptor
|
|
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... |
|
T7569 |
Clebopride malate
|
|
Dopamine Receptor
|
|
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as nausea or vomiting. |
|
T28187 |
Nonabine
|
|
|
|
Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy. |
|
T2574 |
Alizapride hydrochloride
|
Alizapride HCl |
Dopamine Receptor
|
|
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting. |
|
T4568 |
Dolasetron
|
MDL-73147 |
5-HT Receptor
|
|
Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy. |
|
T22313 |
Dolasetron Mesylate
|
Anzemet hydrate,MDL-73147EF |
Others
,
5-HT Receptor
|
|
Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following chemotherapy. |
|
T5009 |
Trimethobenzamide hydrochloride
|
Ro 2-9578,Tribenzagan Hydrochloride |
Dopamine Receptor
,
Influenza Virus
|
|
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
|
T68068 |
Ezlopitant
|
CJ 11974,CJ-11974,CJ11974 |
Neurokinin receptor
|
|
Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain. |
|
T6616 |
Ondansetron hydrochloride
|
SN 307,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran |
5-HT Receptor
|
|
Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy. |
|
T0385 |
Prochlorperazine Maleate
|
Prochlorperazin,Capazine,Prochlorperazine dimaleate salt,Stemetil,Compazine |
Dopamine Receptor
|
|
Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. |
|
T3716 |
Rolapitant
|
SCH619734 |
Neurokinin receptor
|
|
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... |
|
T4562L |
Ramosetron hydrochloride
|
YM 060,YM-060,YM060 |
5-HT Receptor
|
|
Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea. |
|
T2589 |
Dolasetron Mesylate hydrate
|
Dalasetron Mesylate Hydrate |
5-HT Receptor
|
|
Dolasetron Mesylate hydrate (Dalasetron Mesylate Hydrate) , a selective serotonin receptor antagonist, competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radioth... |
|
T0976 |
Propoxur
|
Aprocarb,Propoxure,Baygon |
AChR
,
Antifungal
|
|
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b... |
|
T0944 |
Levamisole hydrochloride
|
(-)-Tetramisole hydrochloride |
Phospholipase
,
AChR
,
Parasite
,
HSV
|
|
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo... |
|
T1110 |
Meclizine dihydrochloride
|
Meclozine dihydrochloride,NSC28728,Meclizine 2HCl |
Apoptosis
,
Histamine Receptor
|
|
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. |
|
T1386 |
Phenazopyridine hydrochloride
|
Urodine,Pyridium,Phenazopyridine HCl |
Sodium Channel
|
|
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red... |
|
T6426 |
Buclizine dihydrochloride
|
Longifene,Buclina,Buclizine HCl,UCB-4445 |
5-HT Receptor
,
AChR
,
Histamine Receptor
|
|
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ... |
|
T4562 |
Ramosetron
|
|
5-HT Receptor
|
|
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondanse... |
|
T34228 |
Quinethazone
|
Quinethazon,Hydromox,Aquamox,Quinethazonum,Chinethazonum |
|
|
Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels. |
|
T10515 |
Anti-Heart Failure Agent 1
|
|
Others
|
|
Anti-Heart Failure Agent 1 is an orally available compound suitable for the treatment of heart failure without inducing vomiting, nausea, and restlessness. |
|
T22393 |
Palonosetron
|
RS25259,RS 25259 197 |
5-HT Receptor
|
|
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). |
|
T15743 |
Levomepromazine
|
Methotrimeprazine |
Others
|
|
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sit... |
|
T38802 |
Trimethobenzamide
|
Ro 2-9578 free base,Trimethobenzamide |
|
|
Trimethobenzamide (Ro 2-9578 free base) is a D2 receptor antagonist and an antiemetic agent. Primarily utilized to mitigate the occurrence of nausea and vomiting, trimethobenzamide effectively blocks the D2 receptor. |
|
T33583 |
Naldemedine
|
S-297995,S297995,Naldemedine,S 297995,S297,995,S 297,995,S297,995;Naldemedine,S-297,995 |
|
|
Naldemedine (S 297995) is a peripheral selective μ-opioid receptor antagonist being developed by Shionogi for the treatment of opioid-induced adverse reactions, including constipation, nausea, and vomiting. They are usua... |
|
T71123 |
RG 12915
|
|
|
|
RG 12915 is a potent, selective 5-HT3 receptor antagonist developed for the treatment of emesis and nausea associated with cancer chemotherapy. |
|
T68371 |
Rolapitant hydrochloride hydrate
|
|
|
|
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant compe... |
|
T72820 |
(R)-Casopitant
|
(R)-GW679769 |
|
|
(R)-Casopitant ((R)-GW679769), an isomer of Casopitant, functions as an NK(1)-receptor antagonist. It has applications in the study of chemotherapy-induced nausea and vomiting [1] [2]. |
|
T83121 |
Anatumomab mafenatox
|
ABR-214936 |
|
|
Anatumomab mafenatox (ABR-214936), a 73 KDa recombinant protein, targets the tumor-associated antigen 5T4 commonly expressed in malignancies. It is a conjugate comprising a modified form of SEA linked to a murine Fab. Th... |
|
T70070 |
Cisapride tartrate
|
|
|
|
Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisa... |
