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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4297 | Flibanserin | BIMT-17BS,Girosa,BIMT-17 | Dopamine Receptor , 5-HT Receptor |
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n... | |||
T6461 | Dapoxetine hydrochloride | LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy | 5-HT Receptor , Serotonin Transporter |
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation. | |||
T0039 | Dapoxetine | Dapoxetina,Dapoxetinum | Others , 5-HT Receptor |
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. | |||
T31081 | CP-866087 | CP 866087,UNII-MDH21334PI,CP-866,087,CP866087 | Opioid Receptor |
CP-866087 is a novel, potent and selective mu-opioid receptor antagonist for the study of female sexual dysfunction. | |||
T31081L | CP 866087 | Opioid Receptor | |
CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction. | |||
T10918 | NEP-IN-1 | Neprilysin | |
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders. | |||
T0384 | Estradiol benzoate | Benzoestrofol,Benzhormovarine,Benovocylin | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. | |||
T72039 | CLK1-IN-3 | DYRK , CDK , Autophagy | |
Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 4... | |||
T0096 | Vardenafil | Vivanza,Levitra,Vardenafil hydrochloride | PDE |
T26516 | ABH Hydrochloride | 6-borono-L-norleucine,ABH HCl | |
ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses. | |||
T71841 | MMV085203 | ||
MMV08520 is a novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites. | |||
T29053 | UK-447841 | UK 447841 | |
UK-447841, a neutral endopeptidase (NEP) inhibitor, is used potentially for the treatment of female sexual dysfunction. | |||
T15749 | LGD-2226 | Androgen Receptor | |
LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle wasting, osteoporosis, and sexual dysfunction. | |||
T27826 | LGD-2941 | LGD 2941,LGD2941 | |
LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome. | |||
T81599 | Orenetide | ||
Orenetide is an innovative peptide-based pharmaceutical designed to rejuvenate sexual desire and associated functions in women suffering from hypoactive sexual desire disorder (HSDD) [1]. | |||
T10230 | MC-4R Agonist 1 | Others | |
MC-4R Agonist 1 is an agonist of human melanocortin-4 receptor (MC-4R) and can be used in the research of sexual dysfunction, obesity, and diabetes. | |||
T24839 | Stampidine | HI-113,HI 113,HI113 | |
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical... | |||
T27400 | Ganaplacide | KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156 | |
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s... | |||
T72380 | PI3K/mTOR Inhibitor-13 | ||
PI3K/mTOR Inhibitor-13, an orally active dual inhibitor targeting phosphoinositol 3-kinase (PI3K) and mTOR kinase, holds potential for treating sexual diseases, solid tumors, and idiopathic pulmonary fibrosis (IPF). | |||
T69627 | Dapivirine HCl | ||
Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promi... | |||
T68836 | ADS-J1 | ||
ADS-J1 is an HIV-1 entry inhibitor that potently inhibits seminal amyloid fibrillization and block fibril-mediated enhancement of viral infection. Semen-derived amyloid fibrils, comprising SEVI (semen-derived enhancer of... | |||
T83544 | (E)-5-Octadecene | (E)-Octadec-5-ene | |
(E)-5-Octadecene ((E)-Octadec-5-ene) serves as a sex pheromone or a chemically related compound, disrupting the sexual attraction of female Chilo suppressalis Walker, commonly known as the rice borer moth [1]. | |||
T62677 | Ganaplacide hydrochloride | ||
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant para... | |||
T62324 | Flibanserin hydrochloride | ||
Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active 5-HT1A receptor agonist (Ki: 1 nM) and 5-HT2A (Ki: 49 nM) receptor antagonist of 5-hydroxytryptamine. Flibanserin hydrochloride has antidepressant and an... | |||
T37924 | 7(Z)-Tricosene | ||
7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila. While it is present in both sexes of some Drosophila species, it is abundant in males, but not female... | |||
T37922 | 7(Z),11(Z)-Pentacosadiene | ||
Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C... | |||
T69215 | Ambrein | ||
Ambrein is a triterpene alcohol that is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodi... | |||
T61572 | FNDR-20123 free base | ||
FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC,... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T1048 | Estradiol | E2,17β-Estradiol,17β-Oestradiol,β-Estradiol | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite |
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be... | |||
T3409 | Plantamajoside | Y0160,C10485 | Others |
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity. | |||
T2A2532 | L-Histidine | Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine | Mitochondrial Metabolism , Endogenous Metabolite |
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-05176 | AMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ... | |||
TMPH-02777 | Mup6 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. Mup6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-... | |||
TMPH-02143 | NR5A1 Protein, Human, Recombinant (His) | Human | E. coli |
Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B an... | |||
TMPY-02393 | Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high... | |||
TMPJ-00762 | ER alpha Protein, Human, Recombinant (His) | Human | E. coli |
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and a... | |||
TMPJ-00796 | Serpin E2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc... | |||
TMPJ-01083 | Serpin E2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea... | |||
TMPJ-01003 | STAT5B Protein, Human, Recombinant (His) | Human | E. coli |
Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ... |