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Search Results for " sexual "

ターゲット

28

阻害剤

3

天然化合物

8

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T4297 Flibanserin BIMT-17BS,Girosa,BIMT-17 Dopamine Receptor , 5-HT Receptor
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...
T6461 Dapoxetine hydrochloride LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy 5-HT Receptor , Serotonin Transporter
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
T0039 Dapoxetine Dapoxetina,Dapoxetinum Others , 5-HT Receptor
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
T31081 CP-866087 CP 866087,UNII-MDH21334PI,CP-866,087,CP866087 Opioid Receptor
CP-866087 is a novel, potent and selective mu-opioid receptor antagonist for the study of female sexual dysfunction.
T31081L CP 866087 Opioid Receptor
CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.
T10918 NEP-IN-1 Neprilysin
NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.
T0384 Estradiol benzoate Benzoestrofol,Benzhormovarine,Benovocylin Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
T72039 CLK1-IN-3 DYRK , CDK , Autophagy
Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 4...
T0096 Vardenafil Vivanza,Levitra,Vardenafil hydrochloride PDE
T26516 ABH Hydrochloride 6-borono-L-norleucine,ABH HCl
ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.
T71841 MMV085203
MMV08520 is a novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites.
T29053 UK-447841 UK 447841
UK-447841, a neutral endopeptidase (NEP) inhibitor, is used potentially for the treatment of female sexual dysfunction.
T15749 LGD-2226 Androgen Receptor
LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle wasting, osteoporosis, and sexual dysfunction.
T27826 LGD-2941 LGD 2941,LGD2941
LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.
T81599 Orenetide
Orenetide is an innovative peptide-based pharmaceutical designed to rejuvenate sexual desire and associated functions in women suffering from hypoactive sexual desire disorder (HSDD) [1].
T10230 MC-4R Agonist 1 Others
MC-4R Agonist 1 is an agonist of human melanocortin-4 receptor (MC-4R) and can be used in the research of sexual dysfunction, obesity, and diabetes.
T24839 Stampidine HI-113,HI 113,HI113
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical...
T27400 Ganaplacide KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s...
T72380 PI3K/mTOR Inhibitor-13
PI3K/mTOR Inhibitor-13, an orally active dual inhibitor targeting phosphoinositol 3-kinase (PI3K) and mTOR kinase, holds potential for treating sexual diseases, solid tumors, and idiopathic pulmonary fibrosis (IPF).
T69627 Dapivirine HCl
Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promi...
T68836 ADS-J1
ADS-J1 is an HIV-1 entry inhibitor that potently inhibits seminal amyloid fibrillization and block fibril-mediated enhancement of viral infection. Semen-derived amyloid fibrils, comprising SEVI (semen-derived enhancer of...
T83544 (E)-5-Octadecene (E)-Octadec-5-ene
(E)-5-Octadecene ((E)-Octadec-5-ene) serves as a sex pheromone or a chemically related compound, disrupting the sexual attraction of female Chilo suppressalis Walker, commonly known as the rice borer moth [1].
T62677 Ganaplacide hydrochloride
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant para...
T62324 Flibanserin hydrochloride
Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active 5-HT1A receptor agonist (Ki: 1 nM) and 5-HT2A (Ki: 49 nM) receptor antagonist of 5-hydroxytryptamine. Flibanserin hydrochloride has antidepressant and an...
T37924 7(Z)-Tricosene
7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila. While it is present in both sexes of some Drosophila species, it is abundant in males, but not female...
T37922 7(Z),11(Z)-Pentacosadiene
Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C...
T69215 Ambrein
Ambrein is a triterpene alcohol that is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodi...
T61572 FNDR-20123 free base
FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC,...

Compounds

Flibanserin
T4297
Synonym: BIMT-17BS,Girosa,BIMT-17
Target: Dopamine Receptor, 5-HT Receptor
Dapoxetine hydrochloride
T6461
Synonym: LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy
Target: 5-HT Receptor, Serotonin Transporter
Dapoxetine
T0039
Synonym: Dapoxetina,Dapoxetinum
Target: Others, 5-HT Receptor
CP-866087
T31081
Synonym: CP 866087,UNII-MDH21334PI,CP-866,087,CP866087
Target: Opioid Receptor
CP 866087
T31081L
Synonym:
Target: Opioid Receptor
NEP-IN-1
T10918
Synonym:
Target: Neprilysin
Estradiol benzoate
T0384
Synonym: Benzoestrofol,Benzhormovarine,Benovocylin
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
CLK1-IN-3
T72039
Synonym:
Target: DYRK, CDK, Autophagy
Vardenafil
T0096
Synonym: Vivanza,Levitra,Vardenafil hydrochloride
Target: PDE
ABH Hydrochloride
T26516
Synonym: 6-borono-L-norleucine,ABH HCl
Target:
MMV085203
T71841
Synonym:
Target:
UK-447841
T29053
Synonym: UK 447841
Target:
LGD-2226
T15749
Synonym:
Target: Androgen Receptor
LGD-2941
T27826
Synonym: LGD 2941,LGD2941
Target:
Orenetide
T81599
Synonym:
Target:
MC-4R Agonist 1
T10230
Synonym:
Target: Others
Stampidine
T24839
Synonym: HI-113,HI 113,HI113
Target:
Ganaplacide
T27400
Synonym: KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
Target:
PI3K/mTOR Inhibitor-13
T72380
Synonym:
Target:
Dapivirine HCl
T69627
Synonym:
Target:
ADS-J1
T68836
Synonym:
Target:
(E)-5-Octadecene
T83544
Synonym: (E)-Octadec-5-ene
Target:
Ganaplacide hydrochloride
T62677
Synonym:
Target:
Flibanserin hydrochloride
T62324
Synonym:
Target:
7(Z)-Tricosene
T37924
Synonym:
Target:
7(Z),11(Z)-Pentacosadiene
T37922
Synonym:
Target:
Ambrein
T69215
Synonym:
Target:
FNDR-20123 free base
T61572
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
T1048 Estradiol E2,17β-Estradiol,17β-Oestradiol,β-Estradiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be...
T3409 Plantamajoside Y0160,C10485 Others
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.
T2A2532 L-Histidine Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine Mitochondrial Metabolism , Endogenous Metabolite
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05176 AMH Protein, Human, Recombinant (His) Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPH-02777 Mup6 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. Mup6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-...
TMPH-02143 NR5A1 Protein, Human, Recombinant (His) Human E. coli
Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B an...
TMPY-02393 Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high...
TMPJ-00762 ER alpha Protein, Human, Recombinant (His) Human E. coli
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and a...
TMPJ-00796 Serpin E2 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPJ-01003 STAT5B Protein, Human, Recombinant (His) Human E. coli
Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ...