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Androgen Receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T8592 CTK8A3536 926228-58-2 98%
CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.
T19450 N-desmethyl Enzalutamide 1242137-16-1 98%
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demon...
T20625 Prochloraz 67747-09-5 98%
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochlora...
T2408 Ostarine 841205-47-8 98%
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, t...
T28502 Ralaniten 1203490-23-6 98%
Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR tran...
TN1067 Galloylpaeoniflorin 122965-41-7 98%
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibti...
T39695 ARD-2128 2222111-87-5 98%
ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protei...
T8860 DSRM-3716 58142-99-7 98%
Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a...
T24943 VPC-14228 19983-28-9 98%
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
T13187 Topterone 60607-35-4 100%
Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in cast...
T67818 BMS-641988 100%
BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.
T2991 3,3'-Diindolylmethane 1968-05-4 100%
3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.
TN1805 Isosilybin B 142796-22-3 100%
Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes t...
T8117 Metenolone acetate 434-05-9 100%
Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow ...
T75129 Luxdegalutamide 2750830-09-0 100%
Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wil...
T6002 Enzalutamide 915087-33-1 100%
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly u...
TQ0214 Dimethylcurcumin 52328-98-0 95.77%
Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferatio...
T6400 AZD3514 1240299-33-5 96.6%
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
T21740 RD162 915087-27-3 97.74%
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
T12146 N-Desmethyl-Apalutamide 1332391-11-3 97.83%
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
CTK8A3536
T8592
CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.
N-desmethyl Enzalutamide
T19450
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demon...
Prochloraz
T20625
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochlora...
Ostarine
T2408
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, t...
Ralaniten
T28502
Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR tran...
Galloylpaeoniflorin
TN1067
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibti...
ARD-2128
T39695
ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protei...
DSRM-3716
T8860
Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a...
VPC-14228
T24943
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
Topterone
T13187
Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in cast...
BMS-641988
T67818
BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.
3,3'-Diindolylmethane
T2991
3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.
Isosilybin B
TN1805
Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes t...
Metenolone acetate
T8117
Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow ...
Luxdegalutamide
T75129
Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wil...
Enzalutamide
T6002
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly u...
Dimethylcurcumin
TQ0214
Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferatio...
AZD3514
T6400
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
RD162
T21740
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
N-Desmethyl-Apalutamide
T12146
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
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