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Search Results for " tension "

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12

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2

天然化合物

6

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1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T2200 Hydroxyzine dihydrochloride Hydroxyzine 2HCl Histamine Receptor
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR...
T0053 Hydroxyzine Pamoate Hydroxyzine embonate,Bobsule,Equipose Histamine Receptor
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca...
T4251 GJ103 sodium salt ATM/ATR
GJ103 sodium salt is an active analog of GJ072, a read-through compound. It has been shown to reduce the surface tension of aqueous solutions, which makes it easier for molecules to move through the solution. It has also...
T15576 Indibulin ZIO 301,D 24851 Apoptosis , Microtubule Associated
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...
T28778 Silperisone HCl RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...
T31620 Emylcamate Emilcamato,Restetal,Nuncital,Psicoplegil,Emylcamat
Emylcamate is an anxiolytic and muscle relaxant. It was advertised for the treatment of anxiety and tension.
T69072 Brovincamine
Brovincamine also known as brovincamine fumarate (BV, Sabromin) was used in Japan mainly as an improver of cerebral circulation and metabolism, and also as an inhibitor of the aggregation of platelets through the cyclic ...
T33765 NVX-108 Dodecafluoropentane,DDFP,Perfluoropentane
NVX-108 is an exceptional oxygen transporter which increases brain tissue oxygen tension (PbtO2) when administered soon after traumatic brain injury (TBI).
T70975 Carsatrin succinate
Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action ...
T37063 Laulimalide
Microtubule stabilizing agent. Potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used). Causes cells to arrest in the prometaphase of the cell cycle, pre...
T38190 Tyr-α-CGRP (rat) (trifluoroacetate salt)
Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.
T71122 Carsatrin (free base)
Carsatrin is purinylpiperazine derivative. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle...
カタログ番号 製品名 別名 ターゲット
T20884 Hydroxyzine Hydroxyzine free base Histamine Receptor
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor.
T3S0401 Piceatannol 3'-O-glucoside Piceatannol 3-glycoside,Quzhaqigan Arginase , NO Synthase
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-01979 SFTPB Protein, Human, Recombinant Human P. pastoris (Yeast)
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearl...
TMPH-01978 SFTPA1 Protein, Human, Recombinant (B2M & His & Myc) Human E. coli
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enh...
TMPY-06810 SFTPB Protein, Human, Recombinant (His) Human CHO Cells
Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by noncil...
TMPH-01241 TOP1 Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via tran...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His) Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (...
カタログ番号 製品名
L7110 Anti-Hypertension Compound Library

678 compounds
678 hypertension-related small molecules for high-throughput and high-content screening.