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Search Results for " thymidine "

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T24609	Thymidine 3',5'-disphosphate	Thymidine 3',5'-biphosphate,pdTp
	pdTp is a highly selective, small-molecule miRNA regulatory complex RISC subunit SND1 inhibitor.
T1513	Telbivudine	NV 02B,L-Thymidine,Epavudine	Others , HBV , Reverse Transcriptase
	Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of tel...		Others , HBV , Reverse Transcriptase
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium	α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP
	Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deo...
T73980	Thymidine 5′-diphosphate
	Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), requiring ATP ...
T29393	3'-Deoxy-4-thiothymidine	Thymidine, 3'-deoxy-4-thio-,Ddthds
	3'-Deoxy-4-thiothymidine can moderately active in protecting HIV-induced cytopathogenicity of MT-2 and CEM cells.
TNU1396	3’,5’-di-O-benzoyl thymidine
	3',5'-di-O-benzoyl thymidine is a Nucleoside Derivative - Other modified nucleoside.
TNU1406	5’-Deoxy-5’-furfurylamino thymidine
	5'-Deoxy-5'-furfurylamino thymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1269	3’-O-(t-Butyldiphenylsilyl)thymidine
	3'-O-(t-Butyldiphenylsilyl)thymidine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.
T73824	Thymidine 3',5'-diphosphate tetrasodium
	Thymidine 3',5'-diphosphate tetrasodium (Deoxythymidine 3′,5′-diphosphate tetrasodium) acts as a selective inhibitor targeting staphylococcal nuclease, tudor domain-containing 1 (SND1, a MicroRNA regulatory complex RISC ...
TNU0727	3’-O-t-Bulyldimethylsilyl thymidine
	Nucleosides - 2’-deoxynucleoside
T40506	5'-O-DMT-dT	5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine
	5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative that finds utility in oligonucleotide synthesis.
TNU1405	5’-Deoxy-5’-(4-morpholinyl)thymidine
	5'-Deoxy-5'-(4-morpholinyl)thymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1606	3’-O-DMTr-thymidine 5’-CE phosphoramidite
	3'-O-DMTr-thymidine 5'-CE phosphoramidite is a Nucleoside Phosphoramidite.
T83837	Rp-Thymidine-5'-O-(1-thiotriphosphate) sodium	Rp-dTTP-α-S
	Rp-Thymidine-5'-O-(1-thiotriphosphate) (Rp-TTP-α-S), an isomer of the sulfur-containing nucleotide derivative TTP-α-S, selectively interacts with HIV-1 reverse transcriptase, exhibiting dissociation constants (Kds) of 45...
T83838	Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium	Sp-TTP-α-S
	Sp-Thymidine-5'-O-(1-thiotriphosphate) (Sp-TTP-α-S), an isomer of the sulfur-containing nucleotide derivative TTP-α-S, exhibits affinity for HIV-1 reverse transcriptase with dissociation constants (Kds) of 2.88, 4.23, an...
TNU1323	3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine
	3',5'-Bis(O-t-butyldimethylsilyl)-4'-C-hydroxymethyl thymidine is a Nucleoside Derivative - 4'-Modified nucleoside; Protected nucleoside w/NH2/OH open.
T1454	Acyclovir	Aciclovir,Acycloguanosine	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , HSV
	Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus fam...
T0863	Idoxuridine	IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection , HSV
	Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.		Antifection , HSV
T27154	Dexelvucitabine	D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase
	Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.		Reverse Transcriptase
T19101	2'-Fluorothymidine	2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine	Others
	2'-Fluorothymidine(2'-Deoxy-2'-fluoro-5-Methyluridine) belongs to the thymidine (TdR) and methyluridine isozymes and is a highly selective substrate for thymidine kinase type 2 (TK2).		Others
TNU0977	4-Thiothymidine		Apoptosis
	4-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside, 5-Modified pyrimidine nucleoside.		Apoptosis
T1663	Deoxythymidine triphosphate		DNA/RNA Synthesis
	Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.		DNA/RNA Synthesis
T19530	Pseudothymidine	5-Methyl-2'-Deoxypseudouridin	Others
	Pseudothymidine is a C-nucleoside analog of thymidine.		Others
T19906	5'-O-Tritylthymidine	M-13,M13,M 13,Monotritylthymidine
	5'-O-Tritylthymidine is a blocker of the formation of the FAK/Mdm-2 complex. 5'-O-Tritylthymidine activates p53 and caspase-8. It also leads to increase detachment and apoptosis in breast and colon cancers.
TNU1111	α-Azidothymidine
	Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides
TNU1149	5’-Azido-5’-deoxythymidine
	Nucleoside Derivatives - 5’-Modified nucleosides, Azido-nucleosides; Drugs and Inhibitors; Inhibitor of mycobacterium tuberculosis monophosphate kinase (TMPKmt)
TNU0946	5'-DMTr-2,2'-anhydrothymidine
	Nucleoside Derivatives - Anhydro-nucleosides, 5-Modified pyrimidine nucleosides; Protected nucleosides with NH2/OH group
TNU1251	5’-Amino-5’-deoxythymidine
	5'-Amino-5'-deoxythymidine is a Nucleoside Derivative - 5'-Deoxy nucleoside; 5'-Modified nucleoside; Amino nucleoside.
TNU1046	5’-O-Triphenylmethyl-3’-deoxy-3’-chlorothymidine
	5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
TNU1322	3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine
	3'-O-t-Bulyldimethylsilyl-4'-C-hydroxymethylthymidine is a Nucleoside Derivative - 4'-Modified nucleoside.
TNU1090	5,6-Dihydrothymidine
	5,6-Dihydrothymidine is a Nucleoside Derivative - 5,6-Dihydrouridine.
TNU1324	4’-Methylthymidine
	4'-Methylthymidine is a Nucleoside Derivative - 4'-Modified nucleoside.
TNU1402	5’-Deoxy-5’-N,N-dimethylaminothymidine
	5'-Deoxy-5'-N,N-dimethylaminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
T40467	Deoxythymidine-5'-triphosphate	dTTP
	Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.
TNU1559	3’-O-Acetylthymidine
	3'-O-Acetylthymidine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
TNU1148	4’,5’-Didehydro-5’-deoxythymidine
	4',5'-Didehydro-5'-deoxythymidine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.
TNU1189	N3-Methylthymidine
	N3-Methylthymidine is a Nucleoside Derivative - N-Methylated nucleoside.
TNU1567	2-Thiothymidine
	2-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside.
T74122	Deoxythymidine-5'-triphosphate sodium hydrate
	Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate, a critical nucleoside triphosphate among four, serves as a trisodium salt in DNA synthesis [1].
T29431	4'-Azidothymidine 5'-triphosphate	Adrt TP,Adrt-TP,AdrtTP
	4'-Azidothymidine 5'-triphosphate exerts selectively action on both reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.
T32816	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine
	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine is a bioactive chemical.
TNU0789	3-epi-Azido-3-deoxythymidine
	3’-N-modified nucleoside; Azido-nucleoside
TNU1395	3’,5’-di-O-acetylthymidine
	3',5'-di-O-acetylthymidine is a Nucleoside Derivative - Other modified nucleoside.
TNU1401	5’-Deoxy-5’-N-methylaminothymidine
	5'-Deoxy-5'-N-methylaminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU0075	2’-Chlorothymidine
	2'-Chlorothymidine is a Halo-nucleoside; 5-modified pyrimidine nucleoside.
TNU1139	2,3’-Anhydrothymidine
	2,3'-Anhydrothymidine is a Nucleoside Derivative - Anhydro-nucleoside.
TNU1049	3’-Deoxy-3’-iodothymidine
	3'-Deoxy-3'-iodothymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
TNU1048	3’-Bromo-3’-deoxythymidine
	3'-Bromo-3'-deoxythymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
TNU1404	5’-Deoxy-5’-N-(2-chloroethyl)aminothymidine
	5'-Deoxy-5'-N-(2-chloroethyl)aminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1156	5’-O-Trityl-2,3’-anhydrothymidine
	5'-O-Trityl-2,3'-anhydrothymidine is a Nucleoside Derivative - Anhydro-nucleoside.

Compounds

Thymidine 3',5'-disphosphate

T24609

Synonym: Thymidine 3',5'-biphosphate,pdTp

Target:

Telbivudine

T1513

Synonym: NV 02B,L-Thymidine,Epavudine

Target: Others, HBV, Reverse Transcriptase

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

Target:

Thymidine 5′-diphosphate

T73980

Synonym:

Target:

3'-Deoxy-4-thiothymidine

T29393

Synonym: Thymidine, 3'-deoxy-4-thio-,Ddthds

Target:

3’,5’-di-O-benzoyl thymidine

TNU1396

Synonym:

Target:

5’-Deoxy-5’-furfurylamino thymidine

TNU1406

Synonym:

Target:

3’-O-(t-Butyldiphenylsilyl)thymidine

TNU1269

Synonym:

Target:

Thymidine 3',5'-diphosphate tetrasodium

T73824

Synonym:

Target:

3’-O-t-Bulyldimethylsilyl thymidine

Synonym: 5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine

Target:

5’-Deoxy-5’-(4-morpholinyl)thymidine

TNU1405

Synonym:

Target:

3’-O-DMTr-thymidine 5’-CE phosphoramidite

TNU1606

Synonym:

Target:

Rp-Thymidine-5'-O-(1-thiotriphosphate) sodium

T83837

Synonym: Rp-dTTP-α-S

Target:

Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium

T83838

Synonym: Sp-TTP-α-S

Target:

3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine

Synonym: Aciclovir,Acycloguanosine

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, HSV

Idoxuridine

T0863

Synonym: IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

Dexelvucitabine

T27154

Synonym: D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC

Target: Reverse Transcriptase

2'-Fluorothymidine

T19101

Synonym: 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine

Deoxythymidine triphosphate

T1663

Synonym:

Target: DNA/RNA Synthesis

Pseudothymidine

T19530

Synonym: 5-Methyl-2'-Deoxypseudouridin

Target: Others

5'-O-Tritylthymidine

T19906

Synonym: M-13,M13,M 13,Monotritylthymidine

5’-Azido-5’-deoxythymidine

TNU1149

Synonym:

Target:

5'-DMTr-2,2'-anhydrothymidine

TNU0946

Synonym:

Target:

5’-Amino-5’-deoxythymidine

TNU1251

Synonym:

Target:

5’-O-Triphenylmethyl-3’-deoxy-3’-chlorothymidine

TNU1046

Synonym:

Target:

3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine

5’-Deoxy-5’-N,N-dimethylaminothymidine

TNU1402

Synonym:

Target:

Deoxythymidine-5'-triphosphate

4’,5’-Didehydro-5’-deoxythymidine

Deoxythymidine-5'-triphosphate sodium hydrate

T74122

Synonym:

Target:

4'-Azidothymidine 5'-triphosphate

T29431

Synonym: Adrt TP,Adrt-TP,AdrtTP

Target:

L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine

T32816

Synonym:

Target:

3-epi-Azido-3-deoxythymidine

TNU0789

Synonym:

Target:

3’,5’-di-O-acetylthymidine

TNU1395

Synonym:

Target:

5’-Deoxy-5’-N-methylaminothymidine

2,3’-Anhydrothymidine

TNU1139

Synonym:

Target:

3’-Deoxy-3’-iodothymidine

TNU1049

Synonym:

Target:

3’-Bromo-3’-deoxythymidine

TNU1048

Synonym:

Target:

5’-Deoxy-5’-N-(2-chloroethyl)aminothymidine

TNU1404

Synonym:

Target:

5’-O-Trityl-2,3’-anhydrothymidine

TNU1156

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
TWP2911	Thymidine	5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others , DNA/RNA Synthesis , Endogenous Metabolite
	1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.		Others , DNA/RNA Synthesis , Endogenous Metabolite
T4730	Thymidine-5'-monophosphate disodium salt	Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT	Others , Endogenous Metabolite
	Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome frag...		Others , Endogenous Metabolite
T21552	5-deoxy Thymidine	5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione	Others
	5-deoxy Thymidine (5'-Deoxythymidine) is a thymidine form which 5' position replaced with hydrogen.5'-deoxy Thymidine was effective against the activity of Bacillus subtilis and Staphylococcus aureus.		Others
T9086	Deoxythymidine-5'-triphosphate trisodium	dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ...		DNA/RNA Synthesis
T80989	Thymidine-5'-diphosphate-L-rhamnose
	Thymidine-5'-diphosphate-L-rhamnose disodium, isolated from Occhromonas malhamensis [1], is a chemical compound.
T4809	Pyrimidine	Metadiazine	Others , Endogenous Metabolite
	Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...		Others , Endogenous Metabolite
TN4944	Santamarine		Caspase
	Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity agai...		Caspase
TMA0918	Neochamaejasmine A		Caspase
	Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating...		Caspase

天然物製品

Thymidine

TWP2911

Synonym: 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Thymidine-5'-monophosphate disodium salt

T4730

Synonym: Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT

Target: Others, Endogenous Metabolite

5-deoxy Thymidine

T21552

Synonym: 5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione

Target: Others

Deoxythymidine-5'-triphosphate trisodium

T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Thymidine-5'-diphosphate-L-rhamnose

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-01386	TK1 Potein, Canine, Recombinant (His)	Canine	E. coli
	Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phas...
TMPJ-00769	TK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identifi...
TMPJ-00905	DTYMK Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis...
TMPJ-00989	MTHFS Protein, Human, Recombinant (His)	Human	E. coli
	5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contr...
TMPY-04542	CDK2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas...