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T19417 |
Urinary Incontinence-Targeting Compound 1
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Others
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Urinary Incontinence-Targeting Compound 1, used in the research of urinary incontinence, is a sulfonanilide derivative. |
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T1049L |
Oxybutynin
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Oxytrol,Ditropan,Oxibutyninum |
Potassium Channel
,
AChR
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Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome. |
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T1049 |
Oxybutynin chloride
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Oxybutynin hydrochloride,Oxybutynin HCl |
Potassium Channel
,
AChR
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Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. |
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T5023 |
Propiverine hydrochloride
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Others
,
Calcium Channel
,
AChR
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Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB). |
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T10952 |
Dabuzalgron
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Ro 115-1240 |
Apoptosis
,
Adrenergic Receptor
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Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by maintaining mitochondrial functi... |
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T1472 |
Trospium chloride
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Spasmex,Sanctura |
AChR
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Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations o... |
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T3126 |
Bethanechol chloride
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(±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride |
AChR
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Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab... |
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T1534 |
Darifenacin hydrobromide
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Darifenacin HBr,UK-88525 |
AChR
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Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome. |
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T29687 |
Afacifenacin
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Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986 |
AChR
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Afacifenacin (SMP-986) fumarate is an M3 muscarinic receptor-selective antagonist used in the study of ischemic heart disease, urinary incontinence and cystitis and other disorders. |
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T28257 |
OPC-51803
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SOU-003,SOU 003,SOU003,OPC51803,OPC 51803 |
Vasopressin Receptor
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OPC-51803 is an orally available nonapeptidylpressor (AVP) V(2) receptor selective agonist for the treatment of urinary incontinence and nocturia. |
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T28257L |
(-)-OPC-51803
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AChR
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(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence. |
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T0111 |
Solifenacin succinate
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YM905 |
AChR
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Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE. |
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T1460 |
Dicyclomine hydrochloride
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AChR
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Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence. |
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T10830 |
CL 316243
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Adrenergic Receptor
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CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL3162... |
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T67956L |
Litoxetine HCl
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litoxetine HCL(86811-09-8 Free base) |
5-HT Receptor
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Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... |
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T10952L |
Dabuzalgron HCl
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R1240,R-450,R450,RO-1151240,R-1240,RO1151240 |
Others
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Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence. |
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T29667 |
Adosopine
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Adosupine |
Others
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Adosopine is a dibenzoazepine which affects urinary bladder hyperreflexia and may be suitable for treating urinary incontinence. |
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T27401 |
Garomefrine HCl
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PNO-49B,NS-49,ABT-232,ABT232,NS49,PNO49B |
Others
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Garomefrine HCl, a α1A-adrenoceptor agonist, is potential for the treatment of urinary incontinence. |
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T26604 |
Alvameline Tartrate
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LU-25-109T,LU 25 109T,LU-25109T,LU 25109T |
Others
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Alvameline Tartrate, a muscarinic M1 receptor agonist and M2/M3 receptor antagonist, is used potentially for treatment of urinary incontinence. |
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T71889 |
Esoxybutynin Chloride
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Others
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Esoxybutynin Chloride is (S)-enantiomer of oxybutynin. Esoxybutynin Chloride exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. Sepracor was developing (S)-oxybutynin, ... |
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T28465 |
PSD-506
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PSD 506,RO 3202904,RO3202904,RO-3202904 |
Others
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PSD-506, a muscarinic M2/M3 antagonist, is used potentially for the treatment of overactive bladder, and urinary incontinence. |
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T71268 |
Esoxybutynin Free Base
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Others
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Esoxybutynin Free Base is (S)-enantiomer of oxybutynin. Esoxybutynin Free Base exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. Sepracor was developing (S)-oxybutynin... |
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T25325 |
Dicyclonon
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LAB 145-138H,BAS 145-138 |
Others
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Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is uti... |
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T70379 |
PF-04479745 tartrate
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Others
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PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measura... |
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T73572 |
NS-8
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Others
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NS-8, a pyrrole derivative, activates the calcium (Ca 2+)-sensitive potassium (K+)-channel, leading to the suppression of the micturition reflex through the reduction of afferent pelvic nerve activity. This compound is v... |
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T72091 |
ADRA1D receptor antagonist 1 free base
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Others
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ADRA1D receptor antagonist 1 (free base) antagonist ( K i =1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC 30 value of 15 nM. ADRA1D receptor antagonist 1 (free... |
