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T1532 |
Pidotimod
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Others
,
Antibacterial
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Pidotimod is a synthetic dipeptide with immunomodulatory properties. |
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T7893 |
Bepotastine
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Bepotastine free base |
Others
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Histamine Receptor
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Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis. |
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T6242 |
Rupatadine Fumarate
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Rinialer,Rupafin,Alergoliber |
PAFR
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Autophagy
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Histamine Receptor
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Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. |
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T6405 |
Bepotastine Besilate
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Talion,TAU 284,Bepreve,Bepotastine Beslilate |
Histamine Receptor
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Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7). |
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T2335 |
Ebastine
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Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 |
Histamine Receptor
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Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss... |
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T20444 |
Hexyl nicotinate
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AI3 15769,AI3-15769,AI315769 |
Others
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Hexyl nicotinate (AI3 15769) is a cutaneous vasodilator and can be used in research on non-immunologic contact urticaria on the scalp, face, and back. |
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T1470 |
Fexofenadine hydrochloride
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Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A |
Histamine Receptor
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Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria. |
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T1553 |
Chlorpheniramine maleate
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NCI-C55265,Chlorphenamine maleate |
Histamine Receptor
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Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. |
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T1097 |
Loratadine
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SCH 29851,Loratidine |
Influenza Virus
,
Histamine Receptor
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Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central ne... |
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T22354 |
Levocetirizine Dihydrochloride
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Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride |
Histamine Receptor
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Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydro... |
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T16730 |
Remibrutinib
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BTK
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Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticar... |
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T0785 |
Dexchlorpheniramine Maleate
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S-(+)-Chlorpheniramine maleate salt |
Dopamine Receptor
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5-HT Receptor
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Norepinephrine
,
Histamine Receptor
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Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d... |
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T0053 |
Hydroxyzine Pamoate
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Hydroxyzine embonate,Bobsule,Equipose |
Histamine Receptor
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Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca... |
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T21390 |
Fexofenadine
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Carboxyterfenadine,Telfast,MDL 16.455,Allegra |
Histamine Receptor
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Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is... |
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T0089 |
Cetirizine dihydrochloride
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P071,UCB P071,Cetirizine DiHCl |
Histamine Receptor
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Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona... |
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T1278 |
Astemizole
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Laridal,Histaminos,Paralergin |
Potassium Channel
,
Histamine Receptor
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Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re... |
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T2200 |
Hydroxyzine dihydrochloride
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Hydroxyzine 2HCl |
Histamine Receptor
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Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... |
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T21112 |
Triprolidine hydrochloride
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295 C 51,Pro-Entra,Entra,Actidilat,Triprolidine hydrochloride anhydrous,Actidil,Pro-Actidil |
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Triprolidine hydrochloride anhydrous, a Histamine H1 antagonist, is used in asthma, allergic rhinitis, and urticaria. |
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T21247 |
Carbinoxamine
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Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine |
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Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an... |
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T0785L |
Dexchlorpheniramine free base
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Polaramine,Dexchlorpheniramine Maleate,Mylaramine |
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Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus. |
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T31396 |
Dexbrompheniramine maleate
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D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral |
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Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the g... |
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T78289 |
Ligelizumab
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QGE 031,Anti-IGHE Recombinant Antibody |
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Ligelizumab (QGE 031), a high-affinity humanized monoclonal anti-IgE antibody, is utilized in the research of chronic spontaneous urticaria [1]. |
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T76919 |
Barzolvolimab
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|
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Barzolvolimab (CDX 0159), a humanized anti-KIT IgG1 monoclonal antibody, specifically and potently inhibits KIT activation by SCF, thereby reducing skin mast cells and disease activity in chronic inducible urticaria [1]. |
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T75276 |
Dexbrompheniramine
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|
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Dexbrompheniramine, an orally active H1 receptor antagonist (antihistamine), mitigates the impacts of the natural chemical histamine in the body. It is utilized in the study of hay fever and urticaria [1]. |
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T73972 |
Fexofenadine Impurity F
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Fexofenadine Impurity F, an impurity present in Fexofenadine, is characterized by its role in the pharmacological profile of this drug. As a H1R antagonist, Fexofenadine serves as an anti-allergic agent, effectively empl... |
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T63965 |
Bepotastine tosylate
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|
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Bepotastine tosylate is a selective, orally active second-generation histamine H1 receptor antagonist that exhibits an inhibitory effect on histamine-mediated upregulation of nerve growth factor (NGF) expression. conjunc... |
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T60521 |
Doxepin
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As a tricyclic antidepressant, Doxepin inhibits the reuptake of serotonin and norepinephrine. Doxepin shows therapeutic effects on atopic dermatitis and chronic urticaria that also improves cognitive processes as well as... |
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TMIH-0271 |
Hydroxyzine dihydrochloride-d4
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(R)-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy-1,1,2,2-d4)ethan-1-ol dihydrochloride |
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Hydroxyzine dihydrochloride-d4 is a deuterated compound of Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride has a CAS number of 2192-20-3. Hydroxyzine hydrochloride is a histamine H1 receptor antagonist that is e... |
