Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T
説明 | TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T |
ターゲット&IC50 | PI3Kγ:29 nM (IC50), Akt:294 nM (IC50) |
In vivo | TASP0415914 demonstrated good potency in a cell-based assay and, furthermore, exhibited in vivo efficacy in a collagen induced arthritis (CIA) model in mice after oral administration[1]. |
分子量 | 323.37 |
分子式 | C13H17N5O3S |
CAS No. | 1292300-75-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (34.02 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TASP0415914 1292300-75-4 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt PI3K inhibit inflammatory PKB stability PI3Kγ oral TASP-0415914 Phosphoinositide 3-kinase Protein kinase B Inhibitor autoimmune TASP 0415914 metabolic inhibitor