Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of β-amyloid (Aβ), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 12,000 | |||
5 mg | 在庫あり | ¥ 28,000 | |||
10 mg | 在庫あり | ¥ 45,500 | |||
25 mg | 在庫あり | ¥ 98,500 | |||
50 mg | 在庫あり | ¥ 147,000 | |||
100 mg | 在庫あり | ¥ 204,500 | |||
500 mg | 在庫あり | ¥ 420,000 |
説明 | LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of β-amyloid (Aβ), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease. |
ターゲット&IC50 | mGluR3:190 nM |
In vitro | LY2389575 hydrochloride (5 μM; 1 h) Induce the increase of Mrc1 level in Microglial cells.[2] |
分子量 | 438.58 |
分子式 | C15H16BrCl3N4 |
CAS No. | 885104-09-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (205.2 mM), Sonication and heating to 60℃ are recommended.
Methanol: 7.5 mg/mL (17.1 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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LY 2389575 hydrochloride 885104-09-6 Neuroscience GluR Beta Amyloid LY 2389575 Hydrochloride LY2389575 Hydrochloride LY-2389575 Hydrochloride Inhibitor inhibitor inhibit