ホーム 計算ツール
代理店ログイン

FAAH

Fatty acid amide hydrolase or FAAH (oleamide hydrolase, anandamide amidohydrolase) is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide in 1993. In humans, it is encoded by the gene FAAH.FAAH is an integral membrane hydrolase with a single N-terminal transmembrane domain. In vitro, FAAH has esterase and amidase activity.In vivo, FAAH is the principal catabolic enzyme for a class of bioactive lipids called the fatty acid amides (FAAs).
Cat. No. 製品名 CAS No. Purity Chemical Structure
T28353 PDP-EA 861891-72-7 98%
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.
T23119 Palmitoylisopropylamide 189939-61-5 98%
Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.
T4323 PF-04457845 1020315-31-4 98%
PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).
TN1965 N-​Benzyllinolenamide 883715-18-2 98%
N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).
T3S2105 N-Benzylpalmitamide 74058-71-2 98%
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the tre...
T67896 CB2R/FAAH modulator-1 928892-60-8 100%
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
T2859 Biochanin A 491-80-5 97.1%
Biochanin A (4-Methylgenistein) is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Biochanin A is a natura...
T6714 URB-597 546141-08-6 97.84%
URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.
T6043 PF-3845 1196109-52-0 98%
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
T11256 FAAH inhibitor 1 326866-17-5 98.05%
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.
T15802 LY2183240 874902-19-9 98.17%
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 27...
T5357 ARN272 488793-85-7 98.23%
ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).
T68492 AM 374 86855-26-7 98.39%
AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM. This compou...
T16515 PF 750 959151-50-9 98.83%
PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
T67747 CB2R/FAAH modulator-3 2876918-67-9 99.02%
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are...
T7688 4-Nonylphenylboronic acid 256383-45-6 99.13%
4-Nonylphenylboronic acid is a inhibitor of FAAH.
T15268 FAAH-IN-2 184475-71-6 99.18%
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).
T77594 VU534 923509-20-0 99.22%
VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related t...
T77513 2-Chlorophenylboronic acid 3900-89-8 99.42%
2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new ...
T1325 Carprofen 53716-49-7 99.45%
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.
PDP-EA
T28353
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.
Palmitoylisopropylamide
T23119
Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.
PF-04457845
T4323
PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).
N-​Benzyllinolenamide
TN1965
N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).
N-Benzylpalmitamide
T3S2105
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the tre...
CB2R/FAAH modulator-1
T67896
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
Biochanin A
T2859
Biochanin A (4-Methylgenistein) is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Biochanin A is a natura...
URB-597
T6714
URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.
PF-3845
T6043
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
FAAH inhibitor 1
T11256
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.
LY2183240
T15802
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 27...
ARN272
T5357
ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).
AM 374
T68492
AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM. This compou...
PF 750
T16515
PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
CB2R/FAAH modulator-3
T67747
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are...
4-Nonylphenylboronic acid
T7688
4-Nonylphenylboronic acid is a inhibitor of FAAH.
FAAH-IN-2
T15268
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).
VU534
T77594
VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related t...
2-Chlorophenylboronic acid
T77513
2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new ...
Carprofen
T1325
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.
1 2