TN1923 |
Mesaconine
|
6792-09-2
|
98%
|
|
Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material bas...
|
TN4675 |
Nortrachelogenin
|
34444-37-6
|
98%
|
|
Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
|
T9962 |
Mepolizumab
|
196078-29-2
|
98%
|
|
Mepolizumab is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomat...
|
TN1660 |
Ganoderic acid C1
|
95311-97-0
|
98%
|
|
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ac...
|
T2S1040 |
Jolkinolide B
|
37905-08-1
|
98%
|
|
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can...
|
TN1475 |
Caulophyllogenin
|
52936-64-8
|
98%
|
|
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammat...
|
TN1936 |
Mogroside III-E
|
88901-37-5
|
98%
|
|
Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in...
|
T1813 |
VGX-1027
|
6501-72-0
|
98%
|
|
VGX-1027(GIT27) is an isoxazole compound with various immunomodulatory properties.
|
T10497 |
Benralizumab
|
1044511-01-4
|
98%
|
|
Benralizumab (MEDI-563) is an IL-5Rα-directed cytolytic monoclonal antibody that induces rapid, direct and nearly complete depletion of eosinophils via enhanced ...
|
T9448 |
IL-17A inhibitor 1
|
2452464-73-0
|
98%
|
|
IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
|
T38105 |
Ixekizumab
|
1143503-69-8
|
98%
|
|
Ixekizumab is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab blocks the bindi...
|
TN1493 |
Chrysosplenol D
|
14965-20-9
|
98%
|
|
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
|
TN4379 |
Kansuinine A
|
57701-86-7
|
98%
|
|
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
|
T34295 |
Resiniferatoxin
|
57444-62-9
|
98%
|
|
Resiniferatoxin inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulat...
|
TN1403 |
Arjunolic acid
|
465-00-9
|
98%
|
|
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
|
T38362 |
Guselkumab
|
1350289-85-8
|
98%
|
|
Guselkumab is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3....
|
TC0036 |
Compound Lup-20(29)-en-3-yl acetate
|
TC0036
|
98%
|
|
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
TQ0218 |
Deoxyandrographolide
|
79233-15-1
|
98%
|
|
Deoxyandrographolide (14-deoxyandrographolide) has an antihyperglycemic effect in vivo. It also potently inhibit the growth of liver (HepG2 and SK-Hep1) and bile...
|
TN1056 |
Mogroside IIe
|
88901-38-6
|
98%
|
|
Mogroside IIe is a bitter triterpenoid saponin which is the main component of unripe Luo Han Guo fruit and a precursor of the commercially available sweetener mo...
|