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NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T0816 Acetohexamide 968-81-0 98%
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) link...
T0809 Dicoumarol 66-76-2 98%
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
T13799 NQO1 substrate 2304503-05-5 98%
NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
T39635 Obafistat 2160582-57-8 98%
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4).
T38684 AKR1C3-IN-4 1284180-11-5 98%
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
T1609 NAD+ 53-84-9 98%
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkag...
T4359 VAS2870 722456-31-7 98%
VAS2870 is an inhibitor of NADPH oxidase (NOX).
T0441 Pasiniazid 2066-89-9 98%
Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.
T16342 KL1333 1800405-30-4 98%
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
T15433 GSK2795039 1415925-18-6
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
T0342 Carvedilol phosphate hemihydrate 610309-89-2 100%
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
T1314 Triclosan 3380-34-5 100%
Triclosan (Irgasan) is an antibacterial and antifungal agent.
T67950 S19-1035 100%
S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC 50 value of 3.04 nM. S19-1035 can be use...
T7374 2-HBA 131359-24-5 95.01%
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T6099 Setanaxib 1218942-37-0 96.72%
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T4529 ASP-9521 1126084-37-4 96.96%
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
TN2126 Quercetin-3-O-glucose-6''-acetate 54542-51-7 97.48%
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
T7191 Diphenyleneiodonium chloride 4673-26-1 98%
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
T7406 AKR1C3-IN-1 327092-81-9 98%
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T8408 GKT136901 955272-06-7 98.29%
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
Acetohexamide
T0816
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) link...
Dicoumarol
T0809
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
NQO1 substrate
T13799
NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
Obafistat
T39635
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4).
AKR1C3-IN-4
T38684
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
NAD+
T1609
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkag...
VAS2870
T4359
VAS2870 is an inhibitor of NADPH oxidase (NOX).
Pasiniazid
T0441
Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.
KL1333
T16342
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
GSK2795039
T15433
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
Carvedilol phosphate hemihydrate
T0342
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
Triclosan
T1314
Triclosan (Irgasan) is an antibacterial and antifungal agent.
S19-1035
T67950
S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC 50 value of 3.04 nM. S19-1035 can be use...
2-HBA
T7374
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
Setanaxib
T6099
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
ASP-9521
T4529
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
Quercetin-3-O-glucose-6''-acetate
TN2126
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
Diphenyleneiodonium chloride
T7191
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
AKR1C3-IN-1
T7406
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
GKT136901
T8408
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
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