| T0809 |
Dicoumarol
|
66-76-2
|
98%
|
|
|
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
|
| T39635 |
Obafistat
|
2160582-57-8
|
98%
|
|
|
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3.
|
| T38684 |
AKR1C3-IN-4
|
1284180-11-5
|
98%
|
|
|
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
|
| T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
100%
|
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
|
| T1314 |
Triclosan
|
3380-34-5
|
100%
|
|
|
Triclosan (Irgasan) is an antibacterial and antifungal agent.
|
| T67950 |
S19-1035
|
|
100%
|
|
|
S19-1035 is a potent and specific inhibitor of aldo-keto reductase 1C3 (AKR1C3), displaying an inhibitory concentration (IC50) of 3.04 nM. It is primarily utiliz...
|
| T7374 |
2-HBA
|
131359-24-5
|
95.01%
|
|
|
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
|
| T4529 |
ASP-9521
|
1126084-37-4
|
96.96%
|
|
|
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
|
| TN2126 |
Quercetin-3-O-glucose-6''-acetate
|
54542-51-7
|
97.48%
|
|
|
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
|
| T4359 |
VAS2870
|
722456-31-7
|
97.49%
|
|
|
VAS2870 is an inhibitor of NADPH oxidase (NOX).
|
| T7191 |
Diphenyleneiodonium chloride
|
4673-26-1
|
98%
|
|
|
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
|
| T7406 |
AKR1C3-IN-1
|
327092-81-9
|
98%
|
|
|
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
|
| T0441 |
Pasiniazid
|
2066-89-9
|
98%
|
|
|
Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.
|
| T13799 |
NQO1 substrate
|
2304503-05-5
|
98.02%
|
|
|
NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
|
| T8408 |
GKT136901
|
955272-06-7
|
98.29%
|
|
|
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
|
| T1609 |
NAD+
|
53-84-9
|
98.35%
|
|
|
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkag...
|
| T15433 |
GSK2795039
|
1415925-18-6
|
98.68%
|
|
|
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
|
| T10353 |
APX-115 free base
|
1270084-92-8
|
99.03%
|
|
|
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM ...
|
| T0816 |
Acetohexamide
|
968-81-0
|
99.19%
|
|
|
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) link...
|
| T16342 |
KL1333
|
1800405-30-4
|
99.27%
|
|
|
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
|
