Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
説明 | AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research. |
ターゲット&IC50 | AKR1C3:0.56 μM (IC50), AKR1C2:15.1 μM (IC50) |
In vitro | The IC50 of AKR1C3-IN-4 for AKR1C2 is 15.1 μM[1]. |
別名 | AKR1C3-IN-4 |
分子量 | 281.23 |
分子式 | C14H10F3NO2 |
CAS No. | 1284180-11-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (355.58 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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AKR1C3-IN-4 1284180-11-5 Metabolism NADPH AKR1C2 resistant CRPC inhibit AKR1C3IN4 AKR1C3 IN 4 cancer AKR1C3 AKR-1C3-IN-4 prostate Inhibitor aldo-keto 1C3 castrate reductase inhibitor