| T3390 |
Obacunone
|
751-03-1
|
98%
|
|
|
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
|
| T2S1040 |
Jolkinolide B
|
37905-08-1
|
98%
|
|
|
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can...
|
| TN1711 |
Gossypetin
|
489-35-0
|
98%
|
|
|
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signal...
|
| TN6814 |
2-Aminooctadecane-1,3,4-Triol
|
13552-11-9
|
98%
|
|
|
2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.
|
| T5172 |
AZ304
|
942507-42-8
|
98%
|
|
|
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).
|
| TN3209 |
3′,4′,7-Trihydroxyflavone
|
2150-11-0
|
98%
|
|
|
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone...
|
| T3123 |
Allicin
|
539-86-6
|
|
|
|
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cel...
|
| TN1448 |
(-)-Bornyl acetate
|
5655-61-8
|
|
|
|
(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal...
|
| T4034 |
Solamargine
|
20311-51-7
|
|
|
|
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown t...
|
| T6380 |
AMG 900
|
945595-80-2
|
|
|
|
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases ...
|
| T3462 |
BMS-582949 hydrochloride
|
912806-16-7
|
|
|
|
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
|
| T4646 |
TA-02
|
1784751-19-4
|
|
|
|
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
|
| T68139 |
Scio-323
|
309913-51-7
|
100%
|
|
|
Scio-323 is an orally available p38 mitogen-activated protein (MAPK) kinase inhibitor.
|
| T3S0209 |
Vincristine
|
57-22-7
|
100%
|
|
|
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-...
|
| T12979 |
BI-3406
|
2230836-55-0
|
100%
|
|
|
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
|
| T4S2326 |
Cornuside
|
131189-57-6
|
100%
|
|
|
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in t...
|
| TN1117 |
Veraguensin
|
19950-55-1
|
100%
|
|
|
Veraguensin is derived from Magnolia sp.. Veraguensin inhibits bone resorption and shows high antileishmanial activity.
|
| T12871 |
Talmapimod
|
309913-83-5
|
100%
|
|
|
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod ...
|
| T6S1572 |
Sauchinone
|
177931-17-8
|
100%
|
|
|
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation o...
|
| T2827 |
Asiatic acid
|
464-92-6
|
96.33%
|
|
|
Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.
|
