Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
説明 | Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs. |
ターゲット&IC50 | p38β:90 nM, p38α:9 nM |
別名 | SCIO-469 |
分子量 | 513 |
分子式 | C27H30ClFN4O3 |
CAS No. | 309913-83-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (185.19 mM)
You can also refer to dose conversion for different animals. 詳細
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Talmapimod 309913-83-5 MAPK p38 MAPK cytotoxicity multiple inhibit tumor SCIO469 cells SCIO-469 Hsp27 Inhibitor phosphorylation SCIO 469 myeloma inhibitor